Sotalol: Effects and Side Effects

How does sotalol work? Sotalol is a so-called class III antiarrhythmic drug (= potassium channel blocker). It prolongs the electrical excitation (action potential) in the atria and ventricles of the heart by inhibiting the outflow of potassium ions from the heart muscle cells. Sotalol thereby prolongs the so-called QT interval. This interval in the ECG … Sotalol: Effects and Side Effects

Hydrochlorothiazide: Effects, Uses & Risks

Hydrochlorothiazide is a diuretic drug and is considered the prototype of thiazide diuretics. The active ingredient is used, among other things, to treat edema. What is hydrochlorothiazide? Hydrochlorothiazide acts on the distal tubules of the nephron. The nephron is the smallest functional unit of the kidney. Hydrochlorothiazide is a diuretic. Diuretics are drugs with a … Hydrochlorothiazide: Effects, Uses & Risks

Fenofibrate: Effects, Uses & Risks

Fenofibrate is, among other fibrates, a variation of clofibric acid. Thereby, it belongs to the lipid-lowering agents like nicotinic acids as well as statins. An increased level of triglycerides is the main spectrum of action of fenofibrate. A cholesterol-lowering effect is less characteristic here, but still present. What is fenofibrate? Fenofibrate (chemical name: 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropionic acid … Fenofibrate: Effects, Uses & Risks

Fibroma: Causes, Symptoms & Treatment

A fibroma is a benign, usually discolored growth in human skin or connective tissue. It is quite harmless in most cases and can be removed if it is bothersome, painful, or displeasing for cosmetic reasons. Fibroma is quite common overall. What is a fibroma? A fibroma usually refers to a benign as well as tumor-like … Fibroma: Causes, Symptoms & Treatment

Bisoprolol Effects and Side Effects

Products Bisoprolol is commercially available in film-coated tablet form as a monopreparation (Concor, generic) and as a fixed combination with hydrochlorothiazide (Concor plus, generic). It has been approved in many countries since 1986. In 2016, a fixed combination with perindopril was approved (Cosyrel). Structure and properties Bisoprolol (C18H31NO4, Mr = 325.4 g/mol) is present in … Bisoprolol Effects and Side Effects

Butterbur: Applications, Treatments, Health Benefits

Butterbur is an ancient medicinal plant whose analgesic, antispasmodic and anti-inflammatory effects were used in ancient times. In the Middle Ages, it was even used against the plague because of its diaphoretic effect. Its main potential lies in migraine prophylaxis, where it is becoming increasingly important today. Occurrence and cultivation of butterbur The growth height … Butterbur: Applications, Treatments, Health Benefits

Contraindication: Treatment, Effect & Risks

A contraindication is when certain factors, such as age, pre-existing conditions or injuries, militate against a particular therapeutic or medical intervention. This medical term is derived from the Latin language of “contra” = “against” and “indicare” = indicate. The technical language also speaks of contraindication. If physicians ignore the presence of a contraindication, the patient … Contraindication: Treatment, Effect & Risks

Beta2-Sympathomimetics

Products Beta2-sympathomimetics are usually commercially available as inhalation preparations (powders, solutions) administered with an inhaler, for example, metered-dose inhaler, diskus, Respimat, Breezhaler, or Ellipta. There are few drugs on the market that can be given perorally. Structure and properties Beta2-sympathomimetics are structurally related to the natural ligands epinephrine and norepinephrine. They may exist as racemates … Beta2-Sympathomimetics

Sotalol

Products Sotalol is commercially available in tablet form (generic). It has been approved in many countries since 1980. The original Sotalex is out of commerce. Structure and properties Sotalol (C12H20N2O3S, Mr = 272.4 g/mol) is present in drugs as sotalol hydrochloride, a racemate and white powder that is readily soluble in water. Sotalol is a … Sotalol