Quincke’s edema, also known as “angioneurotic edema” or angioedema, is an acute swelling of the skin and mucous membrane. This can sometimes affect the subcutaneous connective tissue and subcutaneous fatty tissue. It is an acute and non-painful swelling that can have both allergic and non-allergic causes. Quincke’s edema is therefore not an independent clinical picture, … The Quincke edema
Localization of Quincke’s edema In principle, Quincke’s edema can occur anywhere on the body. However, a specific distribution pattern of the swellings is conspicuous, which leads to a characteristic appearance of the affected persons. It seems to be mainly affected areas where there is a low tissue resistance. These include the eyelids. Depending on the … Localization of Quincke’s edema | The Quincke edema
Associated symptoms of Quincke’s edema Allergic Quincke’s edema can be accompanied by typical symptoms such as hives and itching. The itching then usually affects the entire skin and not just a specific part of the body. Furthermore, redness of the eyes may occur. In the case of non-allergic Quincke’s edema, there may also be accompanying … Associated symptoms of Quincke’s edema | The Quincke edema
Duration of Quincke’s edema Quincke’s edema develops acutely over a few seconds to minutes. With immediate therapy, it usually subsides within a few minutes. It is therefore an acute event overall. However, hereditary or idiopathic Quincke’s edema in particular can occur repeatedly and therefore lead to chronic recurrence, whereas allergic Quincke’s edema can be prevented … Duration of Quincke’s edema | The Quincke edema
What’s bradykinin? Bradykinin is a hormone, which means that it contributes to the communication between cells. It has a similar effect to histamine. In contrast to steroid hormones such as cortisol, for example, it is made up of amino acids strung together, in this case 9 different amino acids. The biological half-life is just 15 … Bradykinin
What is the bradykinin antagonist? Icatibant has recently become available as a bradykinin antagonist for the treatment of hereditary angioedema. This synthetic agent can be injected under the skin in a dissolved form with a syringe during an acute attack and leads to an improvement of symptoms after 1-2 hours. At the molecular level, the … What is the bradykinin antagonist? | Bradykinin
What does bradykinin have to do with Kallikrein? Many kinins are initially present in the blood in their (partially) inactive precursor and must be activated by the enzyme kallikrein in order to be able to exert their effect. Thus, an amino acid must first be split off from the bradykininogen (inactive precursor) by Kallikrein. This … What does bradykinin have to do with Kallikrein? | Bradykinin
Bronchial asthma is a chronic inflammatory disease of the respiratory tract that is associated with obstruction, attacks of shortness of breath and cramping of the bronchial muscles. Bronchial asthma can have different causes, so that an allergic asthma can be distinguished from a non-allergic asthma. This plays an important role in both diagnosis and therapy. … Pulmonary function diagnostics for bronchial asthma
Lung function test for asthma The clinical symptoms are usually already decisive in the diagnosis of asthma. Pulmonary function tests are used here to accurately assess the current lung function and to monitor the course of the therapy. Typically, various tests are performed to determine different pulmonary (lung) parameters. These include, among others: The common … Lung function test for asthma | Pulmonary function diagnostics for bronchial asthma
The diagnosis of angioedema The diagnosis of angioedema is made clinically, i.e. on the basis of the symptoms and through targeted inspection and questioning by the doctor. In known similar cases in the family, genetic testing for C1 esterase inhibition deficiency may be considered as a further diagnostic test. Otherwise, the diagnosis is “ex juvantibus” … The diagnosis of angioedema | The angioedema
Which doctor treats angioedema? If it is an angioedema that occurs at the same time as shortness of breath, an emergency doctor should be called immediately. Otherwise, antihistamines, for example, which are administered in cases of allergic angioedema, are part of the standard repertoire of a medical facility. An allergic reaction can also be triggered … Which doctor treats angioedema? | The angioedema
Introduction Angioedema (swelling of the vessel) or also known as Quincke’s edema, is a sudden swelling of the skin and subcutaneous tissue, sometimes lasting several days. Swelling of the lip, tongue and eye is relatively harmless. On the other hand, swelling of the glottis (the part of the larynx that forms the voice) can be … The angioedema
