Budesonide: Effects, Applications, Side Effects

How budesonide works As a glucocorticoid, the active ingredient budesonide has an anti-allergic, anti-inflammatory and suppressive effect on the immune system (immunosuppressive). It is related to the body’s own stress hormone cortisol, which is also colloquially called cortisone (but “cortisone” actually stands for the inactivated form of the hormone). The active ingredient budesonide is designed … Budesonide: Effects, Applications, Side Effects

Rhinitis Medicamentosa

Symptoms Rhinitis medicamentosa manifests as a stuffy nose with swollen and histologically altered nasal mucosa. Causes It is the result of prolonged use of decongestant nasal medications (sprays, drops, oils, gels) containing active ingredients such as xylometazoline, oxymetazoline, naphazoline, or phenylephrine. Because the nasal mucosa no longer swells on its own and habituation occurs, the … Rhinitis Medicamentosa

Foams

Products Foams are commercially available as pharmaceuticals, cosmetics (personal care products), medical devices, and foods. Some examples are listed below: Rectal foam containing budesonide or mesalazine for inflammatory bowel disease (ulcerative colitis of the rectum). Glucocorticoids and calcipotriol in psoriasis of the skin or scalp. Minoxidil for the treatment of androgenetic hair loss. No drugs: … Foams

Antiasthmatics

1. symptom treatment Beta2-sympathomimetics are derived from epinephrine. They selectively stimulate the adrenergic β2-receptors of bronchial muscles and thus have a bronchospasmolytic effect. For rapid symptom relief, fast-acting agents are usually administered by inhalation, for example, with a metered-dose inhaler or a powder inhaler. They should be used only when needed. An increase in administration … Antiasthmatics

Chronic Obstructive Pulmonary Disease

Symptoms Possible symptoms of chronic obstructive pulmonary disease (COPD) include a chronic cough, mucus production, sputum, shortness of breath, chest tightness, breath sounds, lack of energy, and sleep disturbances. The symptoms often worsen with physical exertion. An acute worsening of chronic symptoms is referred to as an exacerbation. In addition, numerous systemic and extrapulmonary concomitant … Chronic Obstructive Pulmonary Disease

Formoterol

Products Formoterol is commercially available in the form of capsules for inhalation (Foradil) and as a powder inhaler (Oxis). Furthermore, combination products with budesonide (Symbicort Turbuhaler, Vannair Dosieraerosol) and fluticasone propionate are available (Formoterol Dosieraerosol). Formoterol is also combined with beclometasone fixed, see under beclometasone and formoterol (Foster). Furthermore, in 2020, a fixed combination with … Formoterol

Vasomotor Rhinitis

Symptoms Vasomotor rhinitis manifests as a chronic watery-running and/or stuffy nose. Symptoms resemble hay fever but occur year-round and without eye involvement. Both diseases can also occur together. Other possible symptoms include sneezing, itching, headache, frequent swallowing and coughing. Causes and triggers Vasomotor rhinitis is one of the nonallergic and noninfectious rhinitides. The exact causes … Vasomotor Rhinitis

Nasal Polyps

Symptoms Nasal polyps are usually bilateral and localized benign mucosal protrusions of the nasal cavity or sinuses. The leading symptom is nasal constriction leading to a change in voice quality. Other possible symptoms include a watery discharge (rhinorrhea), impaired sense of smell and taste, pain and a feeling of fullness in the head. Nasal polyps … Nasal Polyps

Asthma

Symptoms Asthma causes narrowing and obstruction of the airways, which manifests itself in symptoms such as coughing, shortness of breath, a feeling of tightness, sounds when breathing out, and wheezing (whistling, rattling, rattling). The bronchi become constricted and a thick mucus forms. The disorders occur episodically and frequently at night and early in the morning, … Asthma

Ciclesonide

Products Ciclesonide is administered with a metered-dose inhaler (Alvesco). It has been approved in many countries since 2006. In the United States, it has also been commercially available as a nasal spray for the treatment of allergic rhinitis since 2012 (Zetonna). Structure and properties Ciclesonide (C32H44O7, Mr = 540.7 g/mol) is a prodrug and is … Ciclesonide

Budesonide

Products Budesonide has been approved in many countries since 1988. It is included in numerous medicinal products. Structure and properties Budesonide (C25H34O6, Mr = 430.5 g/mol) is a racemate and exists as a white, crystalline, odorless, tasteless powder that is practically insoluble in water. Effects Budesonide is anti-inflammatory, anti-allergic, and immunosuppressive. Indications Obstructive bronchial disease, … Budesonide

Pseudocroup Causes and Treatment

Symptoms Pseudocroup is usually preceded by a viral infection such as a cold or flu with nonspecific symptoms such as cough, runny nose, and fever. This soon develops into the following typical symptoms: Barking cough (similar to a seal), which worsens with anxiety and excitement Whistling breath sounds, especially when inhaling (inspiratory stridor), difficulty breathing. … Pseudocroup Causes and Treatment