Products Ranolazine is commercially available in the form of sustained-release tablets (Ranexa). It was approved in the United States as early as 2006, in the EU in July 2008, and in many countries in April 2010. Structure and properties Ranolazine or ()–(2, 6-dimethylphenyl)-4(2-hydroxy-3-(2-methoxyphenoxy)-propyl)-1-piperazine acetamide (C24H33N3O4, Mr = 427.54 g/mol) is a piperazine derivative and a … Ranolazine
Substance Nifedipine is a calcium antagonist of the dihydropyridine group and is used to treat high blood pressure (hypertension) and heart sensation (angina pectoris). Fields of application In Germany, nifedipine is used to treat essential hypertension (high blood pressure), hypertensive crises (hypertensive crises), heart sensation (angina pectoris) and Raynaud’s syndrome. Side effects When taking nifedipine, … Nifedipine
General information Amlodipine is an antihypertensive drug. In addition to its use as a basic medication for high blood pressure (arterial hypertension), it is also used to treat chronic tightness in the chest (angina pectoris) and to prevent acute attacks of angina pectoris in Prinzmetal angina. Pharmacologically, it belongs to the class of calcium channel … Amlodipine
What should I watch out for when stopping this medicine? Amlodipine is one of the drugs that lower blood pressure. All drugs in this group must not be suddenly discontinued. Taking the drug reduces the number of so-called receptors in the body, which otherwise keep blood pressure low. The body needs some time to readjust … What should I watch out for when stopping this medicine? | Amlodipine
Contraindications Amlodipine should only be given with special caution to patients with a narrowing of the aortic valve (see aortic valve stenosis), as the drug’s blood pressure-lowering effect can lead to reduced blood flow to the heart, which in turn could trigger a heart attack. In patients with a damaged liver, a lower starting dose … Contraindications | Amlodipine
Are amlodipine tablets halvable? The divisibility of amlodipine tablets depends on the preparation. In the package insert it is noted in each case if the tablets can be divided in half. For example, the tablets of the preparation Amlodipine – 1 A Pharma® 5mg Tablets N can be divided in half. Amlodipine tablets are available … Are amlodipine tablets halvable? | Amlodipine
What are the alternatives to calcium antagonists? The answer to the question what the alternatives to calcium antagonists are depends mainly on the purpose for which the drug is to be taken. In the treatment of high blood pressure, for example, there are several alternatives that can be chosen. In addition to the so-called ACE … What are the alternatives to calcium antagonists? | Calcium antagonists
Calcium antagonists in Parkinson’s disease Calcium antagonists should not be used in people with Parkinson’s disease. Research has shown that certain members of this group of drugs can worsen the symptoms typical of the disease. However, there are also studies that suggest that a particular calcium channel blocker may have a positive effect on the … Calcium antagonists in Parkinson’s disease | Calcium antagonists
Ointment Ointments containing calcium antagonists can be used to relieve pain and discomfort in the anus region. For example, such ointments can help in cases of hemorrhoidal disease (painful blood vessel bulges at the exit of the bowel) and anal fissures (tearing of the intestinal mucosa in the anal canal). It works directly on the … Ointment | Calcium antagonists
Synonyms in a broader sense Calcium channel blocker English: antagonist of calcium Definition Calcium antagonists have an opposite effect to calcium: they prevent calcium from reaching the cells of the heart muscle, the cells of the electrical conduction system (the heart’s electrical conduction system) at the heart and the muscle cells of the blood vessels. … Calcium antagonists
Definition The heart action is divided into two phases, an expulsion phase, in which blood is pumped from the chambers into the blood vessels, and a filling phase, in which the pumped-out heart fills with blood again. The heart works like a suction-pressure pump, so to speak. The expulsion phase is known as systole, the … Diastole too high – Is that dangerous?
Symptoms of excessive diastole Too high blood pressure is not noticed for a very long time and is symptomatically inconspicuous, i.e. if symptoms are noticed, the hypertension is most likely already present for a long time. Typical symptoms are headaches in the early morning, sleep disturbances, dizziness, ringing in the ears, nervousness, palpitations, shortness of … Symptoms of excessive diastole | Diastole too high – Is that dangerous?
