Bevacizumab: Effects, Areas of Application, Side Effects

How bevacizumab works Bevacizumab is a monoclonal antibody that targets VEGF (vascular endothelial growth factor). In this way, its interaction with its binding site (receptor) is prevented. As a result, the formation of new blood vessels (angiogenesis) is inhibited, slowing tumor growth. While normal (healthy) cells eventually lose their ability to divide, this is not … Bevacizumab: Effects, Areas of Application, Side Effects

Causes of polyneuropathy

The causes of polyneuropathy can be manifold. Ultimately, damage to the peripheral nerves results in loss of sensation, tingling paresthesia or even paralysis. In Germany and other western countries, polyneuropathy (PNP) is most frequently triggered by diabetes mellitus and excessive alcohol consumption. Other causes can be poisoning with heavy metals, solvents or medication. Inflammatory diseases … Causes of polyneuropathy

Infectious diseases as a cause of polyneuropathy | Causes of polyneuropathy

Infectious diseases as a cause of polyneuropathy In infectious diseases, a distinction is made between bacterial and viral infections. Borreliosis is one of the bacterial infectious diseases most frequently mentioned in relation to PNP. Borrelia are transmitted by ticks, for example, and can lead to polyneuropathy, which is why tick bites should be well observed … Infectious diseases as a cause of polyneuropathy | Causes of polyneuropathy

Metabolic diseases as a cause of polyneuropathy | Causes of polyneuropathy

Metabolic diseases as a cause of polyneuropathy As a result of metabolic diseases, peripheral nerves can also be damaged. These include functional disorders of the liver (e.g. in liver cirrhosis, hepatitis B, C, etc. ), kidney diseases (uremic polyneuropathy due to waste products produced in the body when kidney function is insufficient) or thyroid diseases. … Metabolic diseases as a cause of polyneuropathy | Causes of polyneuropathy

Stress as a cause of polyneuropathy | Causes of polyneuropathy

Stress as a cause of polyneuropathy Polyneuropathy cannot be caused by stress alone, but nerve pain can still occur due to prolonged stress. These neuralgias are treated by relaxing procedures such as acupuncture, osteopathy but also by medication. Stress is an important and burdening factor for our immune system. In the case of autoimmune diseases … Stress as a cause of polyneuropathy | Causes of polyneuropathy

Other causes of polyneuropathy | Causes of polyneuropathy

Other causes of polyneuropathy Further causes of polyneuropathy can be metabolic diseases, heriditary noxic-toxic effects or borreliosis pathogens, as well as other infectious diseases. In developing countries, leprosy is a common cause of polyneuropathy in addition to the above-mentioned malnutrition. In our latitudes, if the cause of PNP is not known, HIV infection or a … Other causes of polyneuropathy | Causes of polyneuropathy

Sorivudine: Effects, Uses & Risks

Sorivudine is a medical drug that was developed in Japan to treat herpes. Sorivudine was marketed under the trade name Usevir and has been unavailable since a drug scandal killed several people in Japan. It did not even receive approval in Europe, so the drug did not have to be withdrawn from the market. What … Sorivudine: Effects, Uses & Risks

Microtubules: Structure, Function & Diseases

Microtubules are protein filaments that have a tubular structure and, together with actin and intermediate filaments, form the cytoskeleton of eukaryotic cells. They stabilize the cell and also participate in transport and movement within the cell. What are microtubules? Microtubules are tubular polymers whose protein structures are about 24nm in diameter. Together with other filaments, … Microtubules: Structure, Function & Diseases

Listlessness: Causes, Treatment & Help

Listlessness describes a persistent state of lack of energy, the cause of which can be various disorders or medical conditions. Because of the variety of causes, a thorough medical history and individualized treatment are required. Mild forms of listlessness can be prevented and may be cured without medical assistance, while more severe cases require medical … Listlessness: Causes, Treatment & Help