Products Dihydrocodeine is commercially available as sustained-release tablets, drops, and syrup (Codicontin, Paracodin, Escotussin, Macatussin Syrup). It has been approved in many countries since 1957. Structure and properties Dihydrocodeine (C18H23NO3, Mr = 301.4 g/mol) is a hydrogenated derivative of codeine. It is present in drugs as dihydrocodeine thiocyanate, dihydrocodeine hydrochloride, or dihydrocodeine tartrate. Dihydrocodeine tartrate … Dihydrocodeine
Cough syrup as an intoxicant Many antirritant cough syrups contain active ingredients that are psychoactive in high doses and can be abused as intoxicants. Substances include, for example: Opioids such as codeine, dihydrocodeine and ethylmorphine. NMDA antagonists: dextromethorphan Antihistamines such as diphenhydramine and oxomemazine. Phenothiazines: promethazine (out of commerce). Such drugs are unlike other drugs … Misuse of Cough Syrup
Definition The dispensing of licensed medicines is strictly regulated by law in many countries. Drugs may be available by prescription (prescription-only), nonprescription, and over-the-counter. Typical dispensing points are pharmacies, drugstores and doctors’ offices, provided that self-dispensing is permitted by the canton. Category E drugs may also be sold in the retail trade, for example in … Dispensing Categories of Medicinal Products
Products Antitussives are commercially available in the form of tablets, capsules, as cough syrups, and drops, among others. Structure and properties Antitussives do not have a uniform chemical structure. However, many are derived from natural opium alkaloids (opioids). Effects Antitussives have cough-irritating (antitussive) properties. They reduce the frequency and intensity of coughing attacks. Their effects … Antitussives
Dihydrocodeine is an opioid that exerts analgesic and antitussive effects. It has an analgesic potency of 0.2 and is used primarily to treat nonproductive irritable cough. What is dihydrocodeine? Dihydrocodeine is a drug from the opioid group that is used both analgesically (to stop pain) and to stop irritable cough. The analgesic potency of dihydrocodeine … Dihydrocodeine: Effects, Uses & Risks
Background Opioids have been used as painkillers for thousands of years. Initially in the form of opium, the dried milky sap of the opium poppy L. (Papaveraceae). In the early 19th century, the pure opium alkaloid morphine was isolated for the first time and later administered with the newly invented hypodermic needle. In the 20th … Opioids: Drug Effects, Side Effects, Dosage and Uses
Paracodin® is a drug from the group of antitussives (cough suppressants) and is used for unproductive irritable cough. The active ingredient contained in Paracodin is dihydrocodeine. Dihydrocodeine is a derivative of the opium alkaloid morphine and a derivative of codeine, which in turn is prescribed as an antitussive and painkiller. In Germany, Paracodin® falls under … Paracodin®
Interactions with other drugs Dihydrocodeine is a drug that acts in the central nervous system, so it may interact with other substances that act in the brain and spinal cord. If dihydrocodeine is taken simultaneously with central depressant medications such as sedatives, sleeping pills or psychotropic drugs, the respiratory depressive and sedative effect of dehydrocodeine … Interactions with other drugs | Paracodin®
