Muscle Building: Function, Task & Diseases

Muscle building means growth of the musculature, caused by an increased load, such as physical work, sports or special muscle training. In today’s industrialized nations, muscle gain is usually intentional, which is expressed in the numerous fitness studios and sports offers. While moderate muscle gain is not pathological, there are numerous diseases of muscle reduction. … Muscle Building: Function, Task & Diseases

Stanozolol

Products There are no finished drug products containing stanozolol on the market in many countries. Structure and properties Stanozolol (C21H32N2O, Mr = 328.5 g/mol) is a steroid and a pyrazole derivative. It exists as a white, crystalline, and hygroscopic powder that is practically insoluble in water. Effects Stanozolol (ATC A14AA02) is anabolic. Indications for use … Stanozolol

Amphetamines

Products Amphetamines are commercially available as drugs in the form of tablets, sustained-release tablets, capsules, and sustained-release capsules. Structure and properties Amphetamines are derivatives of amphetamine. It is a methylphenethylamine structurally related to endogenous monoamines and stress hormones epinephrine and norepinephrine. Amphetamines are racemates and the –enantiomers. Effects Amphetamines have sympathomimetic, central stimulant, bronchodilator, psychoactive, … Amphetamines

Cathin

Products In many countries, there are currently no registered medicines containing the active ingredient Cathin. Products containing Cathine are not banned, but are subject to prescription and narcotics laws. Structure D-cathine (C9H13NO, Mr = 151.2 g/mol) is a natural substance from the cath (, Celastraceae), which is also produced synthetically. It is a hydroxylated amphetamine … Cathin

Meldonium

Products Meldonium is on the market mainly in Eastern European countries and states of the former Soviet Union in the form of capsules and as an injectable, for example in Russia, Belarus, Ukraine, and Latvia (Mildronate). However, it is not registered in many countries, in the EU and in the USA. Meldonium was developed in … Meldonium

Exemestane

Products Exemestane is commercially available in the form of dragées and film-coated tablets (Aromasin, generics). It has been approved in many countries since 1999. Structure and properties Exemestane (C20H24O2, Mr = 296.4 g/mol), unlike other aromatase inhibitors, has a steroidal structure and resembles the natural substrate androstenedione. It exists as a white to slightly yellowish … Exemestane

Smart Drugs

Effects Smart drugs are pharmaceutical agents that (are intended to) improve the brain’s cognitive abilities: Promote concentration, alertness, attention and receptivity. Increase intelligence and the ability to think Improvement of the imagination Improving understanding and memory Increase creativity This is also referred to as or in English. The effects are based, among other things, on … Smart Drugs

Somatropin

Products Somatropin is commercially available as an injectable from several manufacturers. Recombinant growth hormone has been available since the late 1980s. Biosimilars are approved in some countries. Structure and properties Somatropin is a recombinant polypeptide hormone with a molecular mass of 22 kDa, consisting of 191 amino acids. It corresponds to human growth hormone from … Somatropin

Thiazide Diuretics

Products Thiazide diuretics are commercially available in tablet form. Chlorothiazide (Diuril) and the closely related and more potent hydrochlorothiazide were the first of this group to enter the market in the 1950s (Switzerland: Esidrex, 1958). However, other related thiazide-like diuretics are available (see below). In English, we speak of (thiazide diuretics) and (thiazide-like diuretics). Numerous … Thiazide Diuretics

Beta2-Sympathomimetics

Products Beta2-sympathomimetics are usually commercially available as inhalation preparations (powders, solutions) administered with an inhaler, for example, metered-dose inhaler, diskus, Respimat, Breezhaler, or Ellipta. There are few drugs on the market that can be given perorally. Structure and properties Beta2-sympathomimetics are structurally related to the natural ligands epinephrine and norepinephrine. They may exist as racemates … Beta2-Sympathomimetics

Clostebol

Products No medicines containing clostebol are approved in many countries. Products available in some countries – for example, Italy and Brazil – include Trofodermin cream, a fixed combination with the antibiotic neomycin. Structure and properties Clostebol (C19H27ClO2, Mr = 322.9 g/mol) is a derivative of the male sex hormone testosterone chlorinated at position 4. Trofodermine … Clostebol