Botulinum Toxin: Effects, Uses & Risks

Botulinum toxin is a neurotoxin that has been successfully used as a drug in neurology for many years. However, botulinum toxin has become generally known as Botox, the active agent against expression lines. What exactly is botulinum toxin? And how is botulinum toxin applied? What is botulinum toxin? Botulinum toxin is a neurotoxin that has … Botulinum Toxin: Effects, Uses & Risks

Zolmitriptan

Products Zolmitriptan is commercially available as film-coated tablets, meltable tablets, and as a nasal spray (Zomig, generics). It has been approved in many countries since 1997. Generic versions entered the market in 2012. Structure and properties Zolmitriptan (C16H21N3O2, Mr = 287.4 g/mol) is an indole and oxazolidinone derivative structurally related to serotonin. It exists as … Zolmitriptan

Zopiclone

Products Zopiclone is commercially available in tablet form (Imovane, auto-generics). It has been approved in many countries since 1993. In the United States, the pure -enantiomer eszopiclone is also available (Lunesta). Structure and properties Zopiclone (C17H17ClN6O3, Mr = 388.8 g/mol) is a racemate and belongs to the cyclopyrrolones. It exists as a white to slightly … Zopiclone

Hangover

Symptoms Among the symptoms of a hangover a general feeling of discomfort and misery, drowsiness, dizziness, headache, nausea, vomiting, indigestion, loss of appetite, dry mouth, thirst, sweating, and cognitive and psychological disorders. Causes A hangover usually occurs the morning after excessive alcohol consumption. The condition is further worsened by too little sleep and dehydration. Diagnosis … Hangover

Dihydrocodeine

Products Dihydrocodeine is commercially available as sustained-release tablets, drops, and syrup (Codicontin, Paracodin, Escotussin, Macatussin Syrup). It has been approved in many countries since 1957. Structure and properties Dihydrocodeine (C18H23NO3, Mr = 301.4 g/mol) is a hydrogenated derivative of codeine. It is present in drugs as dihydrocodeine thiocyanate, dihydrocodeine hydrochloride, or dihydrocodeine tartrate. Dihydrocodeine tartrate … Dihydrocodeine

Quetiapine

Products Quetiapine is commercially available in the form of film-coated tablets and sustained-release tablets (Seroquel / XR, generic, auto-generic). It has been approved in many countries since 1999. Generics of film-coated tablets entered the market in 2012, and generics of sustained-release tablets were first registered in 2013. Structure and properties Quetiapine (C21H25N3O2S, Mr = 383.5 … Quetiapine

Mirtazapine: Drug Effects, Side Effects, Dosage and Uses

Products Mirtazapine is commercially available in the form of film-coated tablets and meltable tablets (Remeron, generics). It has been approved in many countries since 1999. Structure and properties Mirtazapine (C17H19N3, Mr = 265.35 g/mol) is a racemate and exists as a white crystalline powder that is sparingly soluble in water. It is structurally closely related … Mirtazapine: Drug Effects, Side Effects, Dosage and Uses

Kratom

Products Kratom is not currently approved as a drug or medical device in many countries. From our point of view, kratom should be classified as a narcotic from a purely technical point of view. However, according to information from Swissmedic, it is not legally a narcotic (as of 1/2015). In 2017, however, the ingredients mitragynine … Kratom

Nabilon

Products Nabilone is commercially available in the United States, the United Kingdom, and Germany, for example, in the form of capsules (Cesamet, Canemes). It is a narcotic drug. In many countries, the drug is not registered. The active ingredient was developed in the 1970s. Structure and properties Nabilone (C24H36O3, Mr = 372.5 g/mol) is a … Nabilon

Benzodiazepines Effects and Side Effects

Products Benzodiazepines are commercially available in the form of tablets, melting tablets, capsules, drops, and injectables, among others (selection). Chlordiazepoxide (Librium), the first benzodiazepine, was synthesized in the 1950s by Leo Sternbach at Hoffmann-La Roche and was launched in 1960. The second active ingredient, the well-known diazepam (Valium), was launched in 1962. Numerous other drugs … Benzodiazepines Effects and Side Effects

Biperides

Products Biperiden is commercially available as tablets, sustained-release tablets, and a solution for injection (Akineton, Akineton retard). It has been approved in many countries since 1958. Structure and properties Biperiden (C21H29NO, Mr = 311.46 g/mol) is present in drugs as biperidene hydrochloride, a white crystalline powder that is sparingly soluble in water. It is a … Biperides

Bismuth, Metronidazole, Tetracycline

Products The fixed combination Pylera with the active ingredients bismuth, metronidazole, and tetracycline was approved in many countries in 2017 in the form of hard capsules. In some countries, it was available much earlier, for example, in the United States since 2006. This treatment is the so-called bismuth quadruple therapy (“BMTO”), which was developed by … Bismuth, Metronidazole, Tetracycline