Thiols

Definition Thiols are organic compounds with the general structure R-SH. They are sulfur analogs of alcohols (R-OH). R can be aliphatic or aromatic. The simplest aliphatic representative is methanethiol, the simplest aromatic is thiophenol (analogue of phenol). Thiols are formally derived from hydrogen sulfide (H2S), in which a hydrogen atom has been replaced by a … Thiols

Inhalation Anesthetics

Products Inhalation anesthetics are commercially available as volatile liquids or as gases for inhalation. Structure and properties Most inhalation anesthetics are halogenated ethers or hydrocarbons. Also used are inorganic compounds such as the gaseous nitrous oxide. The halogenated representatives exist as volatile liquids with a different boiling point. Because of their odor and irritant properties, … Inhalation Anesthetics

Dimethyl Ether

Products Dimethyl ether is found in pharmaceuticals, medical devices and personal care products as an excipient. It should not be confused with dimethyl ether. Structure and properties Dimethyl ether (C2H6O, Mr = 46.1 g/mol) is the simplest representative from the group of ethers with the structure CH3-O-CH3. It exists at standard conditions as a colorless … Dimethyl Ether

Amyl Nitrite

Products Amyl nitrite is commercially available in the form of ampoules (Amyle Nitrite Inhalant USP). The product, available in many countries, is imported from abroad and is not officially approved as a drug. Amyl nitrite is included in the Federal Office of Public Health‘s antidote list and must be stocked in hospitals for the treatment … Amyl Nitrite

Diethyl Ether

Products Diethyl ether is available from specialty retailers as a pure substance. Structure and properties Diethyl ether (C4H10O, Mr = 74.1 g/mol) exists as a clear, colorless, and highly volatile liquid that is soluble in water. A disadvantage of the substance is that it is highly flammable and potentially explosive. The vapors are heavier than … Diethyl Ether

Macrogole

Products Macrogols are commercially available in many countries as powders, granules, and as drinking solutions. The agents are available with or without salts (electrolytes). They have been approved since the 1980s. This article refers to pharmaceuticals. Macrogols such as macrogol 400 are also used as pharmaceutical excipients. Structure and properties Macrogols are mixtures of linear … Macrogole

Intoxicant

Products Legally, a distinction can be made between legal intoxicants (e.g., alcohol, nicotine) and prohibited substances (e.g., many hallucinogens, some amphetamines, opioids). Some substances, such as the opioids or the benzodiazepines, are used as drugs and are legally available with a doctor’s prescription. However, their use as intoxicants is not intended and is therefore referred … Intoxicant

Ether

Definition Ethers are organic molecules with the general structure R1-O-R2, where R1 and R2 are identical for symmetrical ethers. The radicals can be aliphatic or aromatic. Cyclic ethers exist, such as tetrahydrofuran (THF). Ethers can be prepared using, for example, Williamson’s synthesis: R1-X + R2-O–Na+ R1-O-R2 + NaX X stands for halogens Nomenclature Trivial names … Ether

Phenoxyethanol

Products Phenoxyethanol is used as an excipient mainly in semi-solid medicines, for example in creams and lotions. Structure and properties Phenoxyethanol (C8H10O2, Mr = 138.2 g/mol) exists as a colorless, weakly viscous liquid with a slightly aromatic odor of roses and is sparingly soluble in water. It is an aromatic ether and a primary alcohol. … Phenoxyethanol

Ether anesthesia

Definiton – What is ether anesthesia? Ether anesthesia is considered the first form of anesthesia and thus represents the birth of anesthesia. It was first used by an American doctor in 1842. Ether (also known as diethyl ether) is a colourless chemical compound that is gaseous at room temperature. This form of anaesthesia is no … Ether anesthesia