Collagen: Structure, Function & Diseases

Collagen is associated with human connective tissue. In fact, connective tissue is made up of different types of collagen, which is the most important element of connective tissue cells. Teeth, tendons, ligaments, bones, cartilage, blood vessels, and the largest organ in humans – the skin – are all made of a protein called collagen. What … Collagen: Structure, Function & Diseases

Neurotransmitters: Structure, Function & Diseases

Neurotransmitters are something like the couriers of our body. They are biochemical substances that have the task of transmitting signals from one nerve cell (neuron) to the next. Without neurotransmitters, the control of our body would be completely impossible. What are neurotransmitters? The term neurotransmitter already describes the usefulness of these messenger substances very well, … Neurotransmitters: Structure, Function & Diseases

Creatine: Drug Effects, Side Effects, Dosage and Uses

Products Creatine (synonym: creatine) is commercially available as a dietary supplement in powder, tablet, and capsule forms, among others. It has gained popularity since the early 1990s and is now taken by many athletes. Creatine should not be confused with keratin, creatinine or carnitine. Creatinine is a breakdown product of creatine that is excreted in … Creatine: Drug Effects, Side Effects, Dosage and Uses

Gelatin

Products Gelatin is available as a pure substance in grocery stores and in pharmacies or drugstores. It is found in many processed foods, pharmaceuticals, and sweets, among other products. Structure and properties Gelatin is a purified mixture of proteins obtained by either partial acid, alkaline, or enzymatic hydrolysis of collagen. Hydrolysis results in gelling and … Gelatin

Glyphosate

Products Glyphosate was developed by Monsanto in the 1970s (Roundup) and is the world’s best-selling herbicide, with production volumes in the hundreds of thousands of tons. There are also numerous products on the market in many countries. Structure and properties Glyphosate or -(phosphonomethyl)glycine (C3H8NO5P, Mr = 169.1 g/mol) is an -phosphonomethyl derivative of the amino … Glyphosate

Triptorelin

Products Triptorelin is commercially available as an injectable. It has been approved in many countries since 1995. Structure and properties Triptorelin is a more potent derivative of gonadotropin-releasing hormone (GnRH). At position 6, the amino acid glycine has been replaced by D-tryptophan. It is a decapeptide. GnRH: Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly. Triptorelin: Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly Effects Triptorelin (ATC L02AE04) is … Triptorelin

Insulin Glargine

Products Insulin glargine is commercially available as an injectable (Lantus). It has been approved in many countries since 2002. The biosimilar Abasaglar (LY2963016) was approved in the EU in 2014 and in many countries in 2015. The drugs must be stored between 2 to 8°C in a refrigerator. In 2015, Toujeo was additionally approved in … Insulin Glargine

Albiglutide

Products Albiglutide was approved in many countries, in the EU, and in the United States in 2014 in the form of an injectable (Eperzan). Structure and properties Albiglutide is a GLP-1 dimer (fragment of 30 amino acids, 7-36) fused to the human protein albumin. The amino acid alanine at position 8 has been replaced by … Albiglutide

Threonine: Function & Diseases

Threonine is an essential amino acid that can perform several functions in metabolism due to its hydroxyl group. It is a component of most proteins in the body, with a particularly high proportion present in connective tissue. Threonine occurs in four stereoisomeric forms, with only L-threonine with the (2S,3R) configuration being considered for protein construction. … Threonine: Function & Diseases

Tetrahydrofolic Acid: Function & Diseases

Tetrahydrofolic acid plays an important role in the transfer of carbon as coenzyme F in the organism. It is synthesized from folic acid (vitamin B9). Deficiency of THF triggers, among other things, macrocytic anemia, the form triggered by vitamin B12 deficiency being called pernicious anemia. What is tetrahydrofolic acid? Tetrahydrofolic acid functions as an important … Tetrahydrofolic Acid: Function & Diseases

Glycine: Effects, Uses & Risks

Glycine is the simplest alpha-amino acid and thus a component of all proteins. Glycine is particularly present in high concentrations in connective tissue. In the body, it serves as a central switch point between protein, carbohydrate and fat metabolism. What is glycine? Glycine is used as an important ingredient in certain drugs and as a … Glycine: Effects, Uses & Risks

Teduglutide

Products Teduglutide is commercially available as a powder and solvent for solution for injection (Revestive, USA: Gattex). It was approved in the EU and US in 2012 and in many countries in 2016. Structure and properties Teduglutide is an analog of the human polypeptide glucagon-like peptide-2 (GLP-2), which is secreted by L cells in the … Teduglutide