Hirsutism: Treatment, Causes

Brief overview Treatment: Treatment of underlying diseases, replacement with other active ingredients, drug therapy (e.g. with antiandrogens), shaving, epilation, chemical hair removal, laser hair removal, cauterization of hair follicles When to see a doctor? If there is a sudden onset of excessive male body hair, especially if there are other symptoms such as a deeper … Hirsutism: Treatment, Causes

Depilatory

Indications Undesirable or excessive hair growth, for example in hirsutism. Active ingredients Depilatory waxes Eflornithine (Vaniqa)

Antiandrogens

Products Antiandrogens are mainly commercially available in the form of tablets, capsules, and injectables. Among the first steroidal agents was cyproterone acetate, which was patented in the 1960s. Flutamide was the first non-steroidal agent to be approved in the 1980s. Structure and properties A distinction is made between antiandrogens with a steroidal structure (like the … Antiandrogens

Eflornithine

Products Eflornithine is commercially available as a cream in many countries and has been approved since 2003 (Vaniqa). Vaniqa was released in the United States in 2000 and in the EU in 2001. Structure and properties Eflornithine (C6H12F2N2O2, Mr = 182.2 g/mol) is a fluorinated and methylated derivative of the amino acid ornithine. It is … Eflornithine

Hirsutism: Measures and Treatment

Hirsutism is often associated with enormous suffering for affected women, because the excessive body hair and the other signs of masculinization often lead to women feeling themselves as unattractive or being ostracized by others. However, treatment of hirsutism is possible. You can find out how the therapy is done here. Measures against the effects – … Hirsutism: Measures and Treatment

Canrenon

Products Canrenone is commercially available as an injectable (Soldactone). It has been approved in many countries since 1975. Structure and properties Canrenone (C22H28O3, Mr = 340.5 g/mol) is an active metabolite of spironolactone (aldactone) and, unlike the latter, is soluble in water. Canrenone is present in drugs as potassium canrenoate, the potassium salt of canrenoic … Canrenon

Androgenetic Alopecia in Women

Symptoms Increasing diffuse thinning of the hair occurs in the area of the middle parting. In this case, unlike androgenetic alopecia in men, not all hair is lost, but the scalp becomes visible over time. Often, a densely hairy strip remains frontally above the forehead. Dense hair is also still found on the sides and … Androgenetic Alopecia in Women

Ciclosporin

Products Ciclosporin is commercially available as capsules, a drinkable solution, and an infusion concentrate (Sandimmune, Sandimmune Neoral, generics). It has been approved in many countries since 1995. Neoral is the microemulsion formulation that has more stable bioavailability than traditional Sandimmune. In 2016, ciclosporin eye drops were approved (see there). Structure and properties Ciclosporin (C62H111N11O12, Mr … Ciclosporin

Danazol

Products Danazol was commercially available in many countries in the form of capsules and had been approved since 1977 (Danatrol). No finished drug products have since been registered. Structure and properties Danazol (C22H27NO2, Mr = 337.5 g/mol) is an isoxazole derivative of ethisterone related to testosterone. Danazol exists as a white to slightly yellow crystalline … Danazol

Insulinoma

Insulinoma is the most common hormone-producing tumor of the pancreas. It often produces not only insulin, as its name suggests, but also other hormones. In 90% of the cases it is a benign tumor. The most important symptom of insulinoma is the so-called hypoglycemia (“hypoglycemia”). These occur particularly after physical exertion or in the morning … Insulinoma