iron storage disease

Intermediary Metabolism: Function, Role & Diseases

Intermediary metabolism is also referred to as intermediate metabolism. It involves all metabolic processes at the interface of anabolic and catabolic metabolism. Disorders of intermediate metabolic processes are usually due to enzymatic defects and manifest predominantly as storage diseases. What is intermediate metabolism? Intermediate metabolism is all metabolic processes at the interface of anabolic and … Intermediary Metabolism: Function, Role & Diseases

Purpura Chronica Progressiva: Causes, Symptoms & Treatment

Purpura chronica progressiva is a group of diseases that cause punctate skin lesions due to hemorrhage and hemosiderin deposition. Food additives, textile additives, medications and various primary diseases have been identified as causes. Therapy of the skin disease is cause-dependent. What is purpura chronica progressiva? Iron is an essential trace element that is indispensable for … Purpura Chronica Progressiva: Causes, Symptoms & Treatment

Memory Diseases

Definition The term storage disease covers a number of diseases in which the disturbed metabolism leads to deposits of certain substances in the organs or cells. Depending on the substance and organ, storage diseases can vary greatly in their severity and form. Some storage diseases are already apparent at birth and require immediate therapy, whereas … Memory Diseases

Diamond-Blackfan Syndrome: Causes, Symptoms & Treatment

Diamond-Blackfan syndrome is an anemic disorder, although the cause is still unclear. Diamond-Blackfan syndrome can be treated relatively well and sometimes even cured. However, preventive measures are not possible. What is Diamond-Blackfan syndrome? The medical profession refers to Diamond-Blackfan syndrome – also known as erythrogenesis imperfecta or chronic congenital hypoplastic anemia and Diamond-Blackfan anemia (DBA … Diamond-Blackfan Syndrome: Causes, Symptoms & Treatment

Hemochromatosis

Synonyms Primary siderosis, hemosiderosis, siderophilia, iron storage disease English: hematochromatosis Introduction Hemochromatosis is a disease in which there is an increased absorption of iron in the upper small intestine. This increased absorption of iron causes the total iron in the body to rise from 2-6g to values up to 80g. This iron overload results in … Hemochromatosis

Symptoms | Hemochromatosis

Symptoms The symptoms of hemochromatosis are caused by increased iron deposition in various organs, resulting in cell damage. Among other things, there are deposits in: At the beginning of the disease, the affected persons usually do not notice any symptoms or changes. Only after several years do symptoms appear for the first time. Typical are … Symptoms | Hemochromatosis

Diagnosis | Hemochromatosis

Diagnosis If hemochromatosis is symptomatically suspected, blood is taken for initial clarification and it is checked whether the transferrin saturation is above 60% and whether the serum ferritin is above 300ng/ml at the same time. Transferrin serves as an iron transporter in the blood, while ferritin takes over the function of an iron store in … Diagnosis | Hemochromatosis

Therapy | Hemochromatosis

Therapy The therapy of hemochromatosis consists of a reduction of body iron. This is usually achieved with the relatively old therapy of bloodletting. The bloodletting therapy consists of two phases: It is important that these bloodletting procedures take place regularly to ensure that new blood is produced evenly. Dietary measures also play an important role … Therapy | Hemochromatosis

What are the side effects of regular bloodletting? | Hemochromatosis

What are the side effects of regular bloodletting? Typical side effects of bloodletting therapy are caused by the volume that the body then lacks. If these symptoms occur frequently after bloodletting, an infusion can then be given to compensate for the lost fluid. Alternatively, the bloodletting can be divided into several sessions during which less … What are the side effects of regular bloodletting? | Hemochromatosis

Hemochromatosis and diabetes mellitus | Hemochromatosis

Hemochromatosis and diabetes mellitus Iron storage in hemochromatosis affects not only the liver, but many other organs as well. One of the organs affected is the pancreas, which produces the hormone insulin. Insulin is essential for sugar metabolism. The pancreas is damaged by the storage of iron, which can reduce or even stop the production … Hemochromatosis and diabetes mellitus | Hemochromatosis

History | Hemochromatosis

History The first information about the appearance of hemochromatosis was given by a Mr. Armand Trousseau in the 19th century. He described a symptom complex consisting of liver cirrhosis, diabetes and dark skin pigmentation. 20 years later the term hemochromatosis was coined. In the 1970s, the autosomal recessive inheritance was recognized and in the 1990s … History | Hemochromatosis