Minocycline

Products Minocycline is commercially available in the form of film-coated tablets (Minocin). It has been approved in many countries since 1984. Minac capsules are out of commerce. Topical medicines are additionally available in some countries. Structure and properties Minocylcine (C23H27N3O7, Mr = 457.5 g/mol) is present in drugs as minocycline hydrochloride, a yellow, crystalline, hygroscopic … Minocycline

Dispensing Categories of Medicinal Products

Definition The dispensing of licensed medicines is strictly regulated by law in many countries. Drugs may be available by prescription (prescription-only), nonprescription, and over-the-counter. Typical dispensing points are pharmacies, drugstores and doctors’ offices, provided that self-dispensing is permitted by the canton. Category E drugs may also be sold in the retail trade, for example in … Dispensing Categories of Medicinal Products

Enterohepatic Circulation

Definition Pharmaceutical agents are excreted primarily in the urine and, via the liver, in the bile in the stool. When excreted via the bile, they re-enter the small intestine, where they may be reabsorbed. They are transported back to the liver via the portal vein. This repetitive process is called the enterohepatic circulation. It prolongs … Enterohepatic Circulation

Retinoid: Effects, Uses & Risks

Retinoid refers to a group of different active substances, which are collectively known as retinoids. All of these active ingredients are derivatives of vitamin A and have a positive effect on a wide variety of skin diseases. They can be used both externally and internally. However, they can also unfold severe side effects and are … Retinoid: Effects, Uses & Risks

Fordyce Glands

Symptoms Fordyce’s glands are ectopic sebaceous glands located in atypical sites, on the lip or in the oral cavity, and may flow into each other. They are painless and asymptomatic, whitish-yellowish 1-3 mm spots (papules) that are colorfully demarcated from the red of the lip. They occur in up to 30-80% of the population and … Fordyce Glands

Isotretinoin

Products Isotretinoin is commercially available in capsule and gel form (Roaccutane, generics). It has been approved in many countries since 1983 (United States: 1982, Accutane). This article refers to the capsules. See also under isotretinoin gel. Structure and properties Isotretinoin (C20H28O2, Mr = 300.4 g/mol) exists as a yellow to light orange crystalline powder that … Isotretinoin

Isotretinoin Gel

Products Isotretinoin gel has been approved in many countries since 1994 (Roaccutan Gel, Germany: Isotrex Gel). Structure and properties Isotretinoin (C20H28O2, Mr = 300.4 g/mol) exists as a yellow to faint orange crystalline powder that is practically insoluble in water. Especially in solution, it is sensitive to air, heat, and light. Isotretinoin is a stereoisomer … Isotretinoin Gel

Corner of the Mouth Cracks

Symptoms Mouth corner rhagades manifest as inflamed tears in the area of the corners of the mouth. The symptoms are often bilateral and and often involve the adjacent skin. Other symptoms include redness, scaling, pain, itching, crusting and dehydration. Mouth cracks are uncomfortable, bothersome and often slow to heal. Causes Typical causes and risk factors … Corner of the Mouth Cracks

Nummular Eczema

Symptoms Nummular eczema (from Latin , coin) is an inflammatory skin disease that manifests itself in sharply defined, coin-shaped rashes that primarily affect the extensor sides of the legs, arms, and trunk. The areas are weeping, inflamed (reddened), and may become dry, crusted, and itchy. Unlike cutaneous fungus, the lesions are filled in and do … Nummular Eczema

Soft Capsules

Products Various drugs and dietary supplements are commercially available in the form of soft capsules. Active ingredients administered with this dosage form include, for example, pain relievers (e.g., diclofenac, ibuprofen, acetaminophen), retinoids such as isotretinoin, thyroid hormones, cytostatics, ginseng, vitamins, and fatty oils such as fish oil, krill oil, linseed oil, and wheat germ oil. … Soft Capsules

Acne Treatment

Symptoms Acne is a collective name for diseases of the sebaceous gland apparatus and hair follicles. The skin disease occurs predominantly puberty. Not all forms require treatment. However, a minority of patients suffer from severe acne, which should be treated in order to avoid long courses of the disease and scars if necessary. Areas of … Acne Treatment

Actinic Keratosis Treatment

Symptoms Actinic keratosis is a skin disease that manifests itself in various forms. Pink or brown, scaly, highly keratinized patches or papules often form on a reddened base, with sizes ranging from millimeters to centimeters. The lesions can occur all over the body, but usually affect sun-exposed areas such as the head, bald head, ears, … Actinic Keratosis Treatment