Laser Doppler fluxmetry is a diagnostic procedure that provides information about skin microcirculation and is based on the Doppler effect. A helium laser emits light that is reflected by moving erythrocytes in the blood. The amount of reflected light allows conclusions to be made about flow velocity. What is laser Doppler fluxmetry? Laser Doppler fluxmetry … Laser Doppler Fluxmetry: Treatment, Effects & Risks
Definition The presence of a risk factor increases the likelihood of a disease or adverse event. For example, smoking is a recognized risk factor for lung cancer, COPD, and cardiovascular disease. There is a causal (cause-and-effect) relationship. Relationship between risk factor and disease The presence of a risk factor does not necessarily lead to the … Risk Factors
The term eyelid tumor or eyelid tumor covers a whole range of skin growths on the upper or lower limb of the eyes. These tumors can be benign or malignant. What is a eyelid tumor? Eyelid tumors are tumors on the eyelid. Benign eyelid tumors are usually warts, skin sponges, or fatty deposits. Malignant eyelid … Eyelid Tumor: Causes, Symptoms & Treatment
Products Melphalan is commercially available in the form of film-coated tablets and as an injection/infusion preparation (Alkeran). It has been approved in many countries since 1964. Structure and properties Melphalan (C13H18Cl2N2O2, Mr = 305.2 g/mol) is a phenylalanine derivative of nitrogen-lost. It is practically insoluble in water. It exists as a pure L-enantiomer. The racemate … Melphalan
The term choroidal melanoma refers to a malignant tumor formation in the eye. It is a primary tumor that develops directly in the eye itself and usually affects people of advanced age. Choroidal melanoma is the most common cancer of the eye. What is uveal melanoma? The term choroidal melanoma refers to a malignant tumor … Choroidal Melanoma: Causes, Symptoms & Treatment
Most people have moles (birthmarks, nevi). A mole is a benign malformation of the skin. Moles develop mainly during childhood. How many “speckles” are formed depends mainly on genetic predisposition. But UV radiation also plays a role in moles. Therefore, it is important to properly select the sun protection factor of the sunscreen in order … Moles and Sun Protection Factor
Products Trametinib was approved in the form of film-coated tablets in the United States in 2013, in the EU in 2014, and in many countries in 2016 (Mekinist). Structure and properties Trametinib (C26H23FIN5O4, Mr = 615.4 g/mol) is a pyridine and a pyrimidine derivative. It is present in the drug product as trametinib dimethyl sulfoxide, … Trametinib
Products Cobimetinib is commercially available in the form of film-coated tablets (Cotellic). It was approved in many countries in 2015. Structure and properties Cobimetinib (C21H21F3IN3O2, Mr = 531.3 g/mol) is present in the drug as cobimetinib hemifumarate, a white crystalline substance whose solubility is pH-dependent. Effects Cobimetinib (ATC L01XE38) has antitumor and antiproliferative properties. The … Cobimetinib
Products Encorafenib was approved in capsule form in the United States and EU in 2018 and in many countries in 2019 (Braftovi). Structure and properties Encorafenib (C22H27ClFN7O4S, Mr = 540.0 g/mol) exists as a white powder that is somewhat soluble in water only at low pH. Effects Encorafenib (ATC L01XE46) has antitumor and antiproliferative properties. … Encorafenib
Soon it will begin again, the vacation season! The planes will take off again mainly in the direction of the sun. But even those who spend their vacations in this country and treat themselves to regular visits to the swimming lake should urgently take care of their skin. Important sun protection is the be-all and … Sunscreen: Applications & Health Benefits
Products Pembrolizumab was approved as an infusion product in the United States in 2014 and in the EU and many countries in 2015 (Keytruda). Structure and properties Pembrolizumab is a humanized monoclonal antibody. It is an IgG4-κ immunoglobulin with a molecular weight of approximately 149 kDa. Effects Pembrolizumab (ATC L01XC18) has antitumor and immunomodulatory properties. … Pembrolizumab
Symptoms Sunburn manifests itself as an extensive reddening of the skin (erythema), as a 1st degree burn with pain, burning, itching, tightening of the skin and, in severe cases, additionally with skin blisters (transition to a 2nd degree burn). It develops continuously over several hours and reaches a maximum after 12 to 24 hours. The … Sunburn Causes and Remedies
