Metoclopramide: Effects, Uses, Side Effects

How metoclopramide works The active ingredient metoclopramide (MCP) has a stimulating effect on gastric emptying and small intestinal passage (prokinetic) and an emetic (antiemetic) effect. The human body sometimes protects itself from the absorption of toxic substances via the digestive tract by vomiting. As soon as certain substances enter the blood via the stomach or … Metoclopramide: Effects, Uses, Side Effects

Biperides

Products Biperiden is commercially available as tablets, sustained-release tablets, and a solution for injection (Akineton, Akineton retard). It has been approved in many countries since 1958. Structure and properties Biperiden (C21H29NO, Mr = 311.46 g/mol) is present in drugs as biperidene hydrochloride, a white crystalline powder that is sparingly soluble in water. It is a … Biperides

Lysine Acetyl Salicylate

Products Lysine acetyl salicylate is commercially available as powder and injectable (Aspégic, Alcacyl powder, Germany: e.g., Aspirin i.v., Aspisol). It has been approved in many countries since 1973. Migpriv, which is combined with metoclopramide for migraine, was withdrawn from the market in many countries in December 2011 see under Migpriv. Kardégic was withdrawn from the … Lysine Acetyl Salicylate

Antivertiginosa

Products Antivertiginosa are commercially available in the form of tablets, capsules, and drops, among others. The name of the drug group is derived from anti- (against) and vertigo, the Latin technical term for vertigo or spinning. Structure and properties Antivertiginosa do not have a uniform structure because different drug groups are used. Effects The agents … Antivertiginosa

Altitude Sickness

Symptoms Symptoms of altitude sickness are nonspecific and usually appear 6-10 hours after ascent. However, they can also occur after as little as one hour: Headache Dizziness Sleep disorders Loss of appetite Nausea and vomiting Fatigue and tiredness Rapid heartbeat Accelerated breathing, shortness of breath Severe symptoms: Cough Shortness of breath even at rest Tightness … Altitude Sickness

Norovirus

Symptoms Infection with norovirus manifests as gastroenteritis with diarrhea without blood in the stool and/or with violent, even explosive vomiting. Vomiting is more common in children. Furthermore, accompanying symptoms such as nausea, bloating, abdominal pain, abdominal cramps, muscle pain, headache, and mild fever may occur. An asymptomatic course is also possible. The duration of the … Norovirus

Antiemetics: Drugs against Nausea or Vomiting

Products Antiemetics are commercially available in the form of tablets, as melting tablets, as solutions (drops), and injectables, among others. They are also administered as suppositories because peroral administration is not possible. In many countries, the best-known antiemetics include domperidone (Motilium, generic) and meclozine, which, along with caffeine and pyridoxine, is contained in Itinerol B6. … Antiemetics: Drugs against Nausea or Vomiting

Paracetamol: Drug Effects, Side Effects, Dosage and Uses

Products Paracetamol is commercially available in the form of tablets, film-coated tablets, melting tablets, effervescent tablets, as granules, drops, syrups, suppositories, soft capsules, and infusion solution, among others (e.g., Acetalgin, Dafalgan, Panadol, and Tylenol). Paracetamol was not approved until the 1950s (Panadol, Tylenol), although it was developed in the 19th century. It has been registered … Paracetamol: Drug Effects, Side Effects, Dosage and Uses

Dantrolene

Products Dantrolene is commercially available in capsule form and as a solution for injection (dantamacrine, dantrolene). It has been approved in many countries since 1983. It was developed in the 1960s and 70s. This article refers primarily to peroral therapy. Structure and properties Dantrolene (C14H10N4O5, Mr = 314.3 g/mol) is present in the drug as … Dantrolene

Xylazine

Products Xylazine is commercially available as a solution for injection. It is approved exclusively as a veterinary drug in many countries and has been since 1970. Structure and properties Xylazine (C12H16N2S, Mr = 220.3 g/mol) is a thiazine derivative. It exists as a white crystalline powder that is readily soluble in water. In veterinary medicine … Xylazine

Abdominal Pain (Stomach Ache)

Symptoms Abdominal pain manifests as diffuse or clearly localizable pain or cramps in the abdominal area. They may be accompanied by digestive complaints such as diarrhea, flatulence, and vomiting. To be distinguished from this are stomach pains that occur at about the level of the sternum. Causes There are numerous causes of abdominal pain or … Abdominal Pain (Stomach Ache)

Appetite Stimulants

Effects Appetite stimulant Indications Loss of appetite Active ingredients By cause: herbal bitter agents and spices: E.g. wormwood, ginger, take half an hour before meals. Prokinetics: Metoclopramide (Paspertin). Domperidone (Motilium) Antihistamines and anticholinergics: Pizotifen (Mosegor, out of commerce), cyproheptadine (out of commerce in many countries). Antidepressants: E.g. mirtazapine, caution: some antidepressants such as the SSRIs … Appetite Stimulants