Antidepressants

Products Most antidepressants are commercially available in the form of film-coated tablets. In addition, oral solutions (drops), meltable tablets, dispersible tablets, and injectables are also available, among others. The first representatives were developed in the 1950s. It was discovered that the antituberculosis drugs isoniazid and iproniazid (Marsilid, Roche) had antidepressant properties. Both agents are MAO … Antidepressants

Moclobemide

Products Moclobemide is commercially available in the form of film-coated tablets (Aurorix, generics). It has been approved in many countries since 1990. Structure and properties Moclobemide (C13H17ClN2O2, Mr = 268.74 g/mol) is a morpholine and chlorinated benzamide derivative. It exists as a white to yellowish white or reddish powder and is sparingly soluble in water. … Moclobemide

Serotonin Syndrome: Causes and Treatment

Background Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter biosynthesized from the amino acid tryptophan by decarboxylation and hydroxylation. It binds to seven different families of the serotonin receptor (5-HT1 to 5-HT7) and elicits central and peripheral effects that affect mood, behavior, sleep-wake cycle, thermoregulation, pain perception, appetite, vomiting, muscles, and nerves, among others. Serotonin is vasoconstrictive … Serotonin Syndrome: Causes and Treatment

Moclobemide: Effects, Uses & Risks

Moclobemide is an antidepressant from the group of MAO inhibitors (monoamine oxidase inhibitors). It is used in the treatment of depressive disorders (phases of major depression). Moclobemide is also used for anxiety disorders and psychosis. What is moclobemide? Moclobemide is a so-called monoamine oxidase (MAO) inhibitor. It is one of the antidepressants and is primarily … Moclobemide: Effects, Uses & Risks

Antidepressants – What drugs are available?

Thymoleptic, English: antidepressant Definition An antidepressant is a psychotropic drug with antidepressant effects. Besides depression, it is also used in the treatment of e.g. anxiety and obsessive-compulsive disorders, panic attacks, chronic pain, eating disorders, listlessness, sleep disorders and post-traumatic stress syndrome. There are many different classes of active ingredients, which differ in their mechanism of … Antidepressants – What drugs are available?