Nerve Pain: Causes, Treatment

Brief overview Description: Pain caused by damage to or dysfunction of nerves. Treatment: Therapy is based on the cause. Usually the physician treats the pain with medication. Physiotherapy, acupuncture, psychotherapy, surgery are also considered. Symptoms: Typical symptoms are shooting, electrifying, stabbing or burning pain, tingling, numbness as well as increased pain caused by stimuli that … Nerve Pain: Causes, Treatment

Frostbite

Symptoms In localized frostbite, the skin becomes pale, cold, hard, and insensitive to touch and pain. Only when it warms and thaws does redness appear and severe, pulsating pain, burning, and tingling set in. In addition, edema and blisters may form and, in a severe course, tissue dies. Often affected are exposed parts of the … Frostbite

Stavudine

Products Stavudine is commercially available in capsule form (Zerit). It has been approved in many countries since 1996. Structure and properties Stavudine (C10H12N2O4, Mr = 224.2 g/mol) is a thymidine analog with a missing 3′-hydroxy group. It is a prodrug that is biotransformed intracellularly to the active metabolite stavudine triphosphate. Stavudine exists as a white … Stavudine

Carboplatin

Products Carboplatin is commercially available as an infusion solution (paraplatin, generic). It has been approved in many countries since 1986. Structure and properties Carboplatin (C6H12N2O4Pt, Mr = 371.3 g/mol) is a platinum compound. It exists as a colorless crystalline powder that is sparingly soluble in water. Carboplatin is structurally related to cisplatin, the first platinum … Carboplatin

Dapsone

Products Dapsone is approved in Germany in tablet form (Dapsone-Fatol). In the USA, it is additionally on the market as a gel for the treatment of acne (Aczone). No preparations are currently registered in many countries. Structure and properties Dapsone or 4,4′-diaminodiphenylsulfone (C12H12N2O2S, Mr = 248.3 g/mol) is a sulfone and aniline derivative with structural … Dapsone

Pertuzumab

Products Pertuzumab is commercially available as a concentrate for the preparation of an infusion solution (Perjeta). It was approved in many countries in 2012. Structure and properties Pertuzumab is a recombinant humanized IgG1 monoclonal antibody. It was developed as a successor to trastuzumab (Herceptin). Effects Pertuzumab (ATC L01XC13) has cytostatic and antiproliferative properties. The effects … Pertuzumab

Trigeminal Neuralgia: Causes and Treatment

Symptoms Flashing, stabbing, sharp, short-lasting pain in the cheek, lips, chin, and lower jaw Muscle spasms (“tic douloureux”). Hypersensitivity to touch Weight loss: chewing causes pain, patients stop eating Usually unilateral, very rarely bilateral. Trigger: Touching, washing, shaving, smoking, talking, brushing teeth, eating and the like. Trigger zones: Small areas in the nasolabial fold on … Trigeminal Neuralgia: Causes and Treatment

Didanosine

Products Didanosine was commercially available in the form of capsules (Videx EC). It was first approved in 1991 as the second HIV drug after AZT (EC = enteric coated, capsules filled with enteric granules). Structure and properties Didanosine (C10H12N4O3, Mr = 236.2 g/mol) corresponds to 2′,3′-dideoxyinosine, a synthetic nucleoside analog of deoxyadenosine. The 3′-hydroxy group … Didanosine

Cramps despite magnesium intake – What can I do?

Introduction – Cramps despite magnesium Fighting is generally understood to be the temporary, usually painful, contraction of muscles. One of the most common reasons for cramps is a lack of magnesium. If the cramps occur despite magnesium intake, this can have many different causes: Firstly, paraphysiological cramps after overexertion and are usually the result of … Cramps despite magnesium intake – What can I do?

Prognosis | Cramps despite magnesium intake – What can I do?

Prognosis With an appropriate healthy lifestyle and a balanced diet, cramps in the calf and feet disappear within a short time. If they persist, a neurological clarification is necessary. Daily exercise and massages also have a positive effect. These can also be prescribed by a doctor and are then performed by a physiotherapist. Neurological diseases … Prognosis | Cramps despite magnesium intake – What can I do?

Cramps despite magnesium intake during pregnancy | Cramps despite magnesium intake – What can I do?

Cramps despite magnesium intake during pregnancy Pregnant women often experience fluctuations in the concentration of electrolytes during pregnancy. A magnesium deficiency is often responsible for cramps, especially in the legs. If cramps occur despite magnesium intake, the dose of magnesium should perhaps be reconsidered, as it may not be sufficient. If cramps occur despite the … Cramps despite magnesium intake during pregnancy | Cramps despite magnesium intake – What can I do?