Tramadol and Paracetamol

Products The combination drug containing the active ingredients tramadol and paracetamol is commercially available in the form of film-coated tablets (Zaldiar). It has been approved in many countries since 2002. In 2014, generic versions went on sale. The effervescent tablets are out of trade. Structure and properties Tramadol (C16H25NO2, Mr = 263.38 g/mol) is a … Tramadol and Paracetamol

Breakthrough Pain

Symptoms Breakthrough pain is acute and transient pain that occurs against a background of continuous pain management. It is an acute exacerbation that is most common in chronic disease and especially in cancer. The pain is usually sudden, acute, and intense. Causes The exact causes are not always known. Breakthrough pain may occur as a … Breakthrough Pain

Morphine: Drug Effects, Side Effects, Dosage and Uses

Products Morphine is available in many countries in various dosage forms, including tablets, capsules, oral suspension, syrup, morphine drops, suppositories, and injectables. It is also prepared in pharmacies as an extemporaneous formulation. Structure and properties Morphine (C17H19NO3, Mr = 285.3 g/mol) is present in drugs mainly as morphine hydrochloride and as morphine sulfate pentahydrate. These … Morphine: Drug Effects, Side Effects, Dosage and Uses

Can taking Aspirin® and alcohol be fatal? | Aspirin and alcohol – is that compatible?

Can taking Aspirin® and alcohol be fatal? The combined intake of Aspirin® and alcohol can lead to severe side effects which can be fatal. This is especially the case if there is extensive gastric bleeding. Due to a considerable loss of blood, life-threatening conditions can quickly arise in these cases. This is also the case … Can taking Aspirin® and alcohol be fatal? | Aspirin and alcohol – is that compatible?

Prophylaxis | Aspirin and alcohol – is that compatible?

Prophylaxis There is no specific prophylaxis against side effects which can be associated with the simultaneous intake of Aspirin® and alcohol. In general, it is not advisable to take both substances at close intervals or to take both substances regularly. Since other pain medication in combination with alcohol has a more favourable profile, a change … Prophylaxis | Aspirin and alcohol – is that compatible?

Interactions | Aspirin

Interactions Interactions of Aspirin® , i.e. interactions with other drugs, result from the competition for transport proteins in the blood. This applies especially to those drugs which, like Aspirin® , are transported to a target predominantly by binding to such proteins in the blood:Examples include oral antidiabetics (drugs against diabetes mellitus, the most common are … Interactions | Aspirin

Dosage | Aspirin

Dosage The dosage of Aspirin® is related to the desired effect. Higher doses have a stronger analgesic, anti-inflammatory and antipyretic effect. However, the number and severity of side effects increases, especially with long-term use. This is important, for example, when diluting the blood with Aspirin®. The tablets must be taken daily for months, sometimes years. … Dosage | Aspirin

Aspirin

Synonyms in a broader sense ASS, acetylsalicylic acid, (COX inhibitors, NSAIDs, non-steroidal anti-inflammatory drugs, non-steroidal analgesics, non-opioid analgesics, NSAIDs). The name of the synthetically produced active ingredient usually contained in Aspirin®, “acetylsalicylic acid”, comes from the origin of the mother substance “salicylic acid” from the leaves and flowers of plants – the main source is … Aspirin

Fields of application | Aspirin

Fields of application Typical areas of application for Aspirin® are Pain Headaches Migraine Fever Flu Aspirin® also has a blood-thinning effect. The reason for this is an inhibition of blood platelets or thrombocytes. These normally stick together at the beginning of blood clotting and thus create the first clot. However, for this to happen, they … Fields of application | Aspirin

Metabolization | Aspirin

Metabolization What happens to Aspirin® in the body? Aspirin® is taken orally, i.e. as a tablet. The absorption into the blood starts in the stomach, which explains the early onset of action compared to other analgesics: the highest concentration in the blood is reached after only 25 minutes. The reason for this is the chemical … Metabolization | Aspirin