Lisinopril: Drug Effects, Side Effects, Dosage and Uses

Products Lisinopril is commercially available in tablet form as a monopreparation (Zestril, generic) and as a fixed combination with hydrochlorothiazide (Zestoretic, generic). It has been approved in many countries since 1989. Structure and properties Lisinopril (C21H31N3O5, Mr = 405.49 g/mol) is present in drugs as lisinopril dihydrate, a white crystalline powder that is soluble in … Lisinopril: Drug Effects, Side Effects, Dosage and Uses

Gelatin

Products Gelatin is available as a pure substance in grocery stores and in pharmacies or drugstores. It is found in many processed foods, pharmaceuticals, and sweets, among other products. Structure and properties Gelatin is a purified mixture of proteins obtained by either partial acid, alkaline, or enzymatic hydrolysis of collagen. Hydrolysis results in gelling and … Gelatin

Captopril Effects and Side Effects

Products Captopril was approved in many countries in 1980 as the first active ingredient in the ACE inhibitor group. The original Lopirin is now off the market. Generic products are available in tablet form. Structure and properties Captopril (C9H15NO3S, Mr = 217.3 g/mol) is a derivative of the amino acid proline. It exists as a … Captopril Effects and Side Effects

Gliptine

Products Gliptins are commercially available in the form of film-coated tablets. Sitagliptin (Januvia) was the first representative to be approved in the United States in 2006. Today, various active ingredients and combination products are commercially available (see below). They are also called dipeptidyl peptidase-4 inhibitors. Structure and properties Some gliptins have a proline-like structure because … Gliptine

Gluten

Products Gluten is found as a powder in commerce (e.g., Morga) and in flours. Structure and properties Gluten is a complex mixture of water-insoluble proteins found in the endosperm of cereal grains, particularly wheat, spelt, rye, and barley. Gluten is rich in the amino acids glutamine and proline and serves as a storage protein. In … Gluten

Insulin Aspart

Products Insulin aspart is marketed as an injectable (NovoRapid, USA: NovoLog). It has been approved in many countries since 1999. The fixed combination IDegAsp (insulin aspart + insulin degludec, Ryzodeg) was registered in many countries and in the EU in 2013. In 2017, Fiasp ultra-fast-acting, a very fast-acting insulin aspart, was also approved. With the … Insulin Aspart

Celiac

Background The “gluten” protein is a protein mixture found in many grains such as wheat, rye, barley, and spelt. Its high content of the amino acids glutamine and proline makes gluten resistant to breakdown by digestive enzymes in the intestines, which contributes to the inflammatory response. Gluten has elastic properties and is therefore an important … Celiac

Rapastinel

Products Rapastinel is in clinical development at Allergan and is not yet commercially available. It was originally developed by Naurex Inc, a pharmaceutical company based in Evanston, Ill. Naurex was acquired by Allergan in 2015 for more than half a billion US$. Other companies are also working on glyxins. Structure and properties Rapastinel (C18H31N5O6, Mr … Rapastinel

Amino Acids

Products Some preparations containing amino acids are approved as medicinal products. These include, for example, methionine tablets or infusion preparations for parenteral nutrition. Amino acids are also marketed as dietary supplements, such as lysine, arginine, glutamine, and cysteine tablets. Protein powders such as whey protein can also be counted as amino acid supplements. Amino acids … Amino Acids

Proline: Function & Diseases

Proline is an amino acid. The human organism is able to produce proline based on glutamic acid. It is a non-essential amino acid. What is proline? Proline belongs to the non-essential, secondary amino acids or imino acids in the human organism, as it can produce proline independently. Nevertheless, prolonged and chronic diseases, as well as … Proline: Function & Diseases

HIV Protease Inhibitor

Products Most HIV protease inhibitors are commercially available in tablet or capsule form. In addition, a few liquid dosage forms are available for ingestion. Saquinavir (Invirase) was the first to be lanicized in 1995. Structure and properties The first HIV protease inhibitors were modeled on the natural peptide substrate of the HIV protease. The protease … HIV Protease Inhibitor

Amino acids list

Amino acids are the basic substances of proteins and there are 20 different amino acids from which the body can form many different proteins among other substances. The 20 amino acids can be divided into two groups, the essential and the non-essential amino acids. There are eight essential amino acids, isoleucine, leucine, lysine, methionine, phenylalanine, … Amino acids list