What is a stem cell transplant? A transplant basically refers to the transfer of tissue between two organisms, the donor and the recipient. The donor and recipient can be the same person (autologous transplantation) or two different people (allogeneic transplantation). This is also the case with stem cell transplants – a form of therapy that … Stem cell transplantation: Reasons and process
Introduction Thalassemia is a hereditary disease of the red blood cells. It involves a defect in hemoglobin, an iron-containing protein complex responsible for the red blood cells’ ability to bind oxygen. It is not produced in sufficient quantities or is broken down in greater quantities, resulting in a haemoglobin deficiency. Depending on the severity of … Thalassemia
Prognosis The prognosis of thalassemia is strongly dependent on the severity of the disease. Patients with mild forms can usually lead a normal life without major restrictions. In the severe form of the disease, the effectiveness of the therapy and any complications that arise are important. The prognostic prospects of the disease in the individual … Prognosis | Thalassemia
Definition A stem cell transplantation is the transfer of stem cells from a donor to a recipient. Stem cells are body cells that are the origin for the development of other cells. They have the ability to differentiate into, for example, muscle, nerve and blood cells. Mature stem cells are found in more than 20 … Stem Cell Transplantation
Procedure of a stem cell transplantation Stem cell transplantation from the perspective of the recipient begins with so-called conditioning. This is a preparatory phase, which serves to destroy malignant cells in the bone marrow and is accompanied by a suppression of the body’s own immune system. Chemo- and radiotherapy as well as antibody therapies are … Procedure of a stem cell transplantation | Stem Cell Transplantation
Complications and risks of stem cell transplantation Survival rates after allogeneic or autologous stem cell transplantation have continuously increased in recent years. This is due to increasingly safe transplants and a decrease in transplant-associated mortality. However, the survival rate depends on many factors. Stage of disease and form of disease, age and constitution, as well … Complications and risks of stem cell transplantation | Stem Cell Transplantation
Introduction In organ transplantation, a diseased organ of a patient is replaced by the same organ from a donor. This organ donor is usually recently deceased and has agreed to the removal of his organs if his death can be proven beyond doubt. Living people can also be considered as donors if a special relationship … Organ Transplantation
Bone Marrow Donation Bone marrow donation plays an important role in the therapy of malignant tumor diseases affecting the hematopoietic system. Examples of such diseases are: acute leukemias, chronic myeloid leukemia (CML), Hodgkin’s lymphoma or non-Hodgkin’s lymphoma, but also aplastic anemia and thalassemia, which are not tumor diseases. The bone marrow contains stem cells that … Bone Marrow Donation | Organ Transplantation
Liver Transplantation Every year, approximately 1000 patients in Germany are treated with new liver parts. The donor organs are mostly from deceased people, whereby one liver can be divided between two needy patients. A living donation is also possible to a certain extent. This way, parents can donate parts of their liver for their sick … Liver Transplantation | Organ Transplantation
Lung Transplantation In a lung transplantation, only one or more lung lobes, a whole lung or both lobes can be used. The choice between the different options is made individually depending on the previous disease. The following diseases most frequently require lung transplantation in the final stage: therapy-resistant sarcoidosis, COPD (chronic obstructive pulmonary disease), pulmonary … Lung Transplantation | Organ Transplantation
Procedure of organ donation If an organ donor dies, their personal data will be forwarded to the German Foundation for Organ Transplantation (DSO), which in turn contacts the highest authority called Eurotransplant. Eurotransplant is a medical center that coordinates the allocation of organ transplants throughout Europe. Once a suitable organ has been found for a … Procedure of organ donation | Organ Transplantation
Definition – What is the HLA? In medicine, the abbreviation HLA stands for Human Leukocyte Antigen. The HLA are a group of molecules consisting of a protein portion and a carbohydrate portion. Therefore they are called glycoprotein. The HLA are found on the surface of every single body cell and also on the surfaces of … HLA – Human Leukocyte Antigen
