Products Insulin degludec is commercially available as a solution for injection (Tresiba). It is also combined fixed with insulin aspart (Ryzodeg, see under IDegAsp). It was newly approved in many countries in March 2013. In 2014, a fixed combination with liraglutide was registered (Xultophy); see under IDegLira. Structure and properties Insulin degludec has essentially the … Insulin Degludec
Products Insulin detemir is commercially available as an injectable (Levemir). It has been approved in many countries since 2003. Structure and properties Insulin detemir (C267H402O76N64S6, Mr = 5916.9 g/mol) has an identical primary sequence to human insulin except for the removed threonine at position B30 of the B chain and an added molecule of myristic … Insulin Detemir
Threonine is an essential amino acid that can perform several functions in metabolism due to its hydroxyl group. It is a component of most proteins in the body, with a particularly high proportion present in connective tissue. Threonine occurs in four stereoisomeric forms, with only L-threonine with the (2S,3R) configuration being considered for protein construction. … Threonine: Function & Diseases
Products Rapastinel is in clinical development at Allergan and is not yet commercially available. It was originally developed by Naurex Inc, a pharmaceutical company based in Evanston, Ill. Naurex was acquired by Allergan in 2015 for more than half a billion US$. Other companies are also working on glyxins. Structure and properties Rapastinel (C18H31N5O6, Mr … Rapastinel
Products Porcine insulin was commercially available as an injectable (insulin hypurin porcine). It was available as rapid-acting insulin, isophane insulin, and mixed insulin. Porcine insulin is stored in a refrigerator. It should not be frozen or exposed to high heat. Insulin Hypurin Porcine was withdrawn from the market in many countries on October 31, 2015. … Porcine Insulin
Products Some preparations containing amino acids are approved as medicinal products. These include, for example, methionine tablets or infusion preparations for parenteral nutrition. Amino acids are also marketed as dietary supplements, such as lysine, arginine, glutamine, and cysteine tablets. Protein powders such as whey protein can also be counted as amino acid supplements. Amino acids … Amino Acids
Products Osimertinib was approved in the United States in 2015 and in the EU and Switzerland in 2016 in film-coated tablet form (Tagrisso). Structure and properties Osimertinib exists in the drug product as osimertinib mesilate (C28H33N7O2 – CH4O3S, Mr = 596 g/mol). It is a methylindole, aniline and pyrimidine derivative. Effects Osimertinib (ATC L01XE35) has … Osimertinib
Amino acids are the basic substances of proteins and there are 20 different amino acids from which the body can form many different proteins among other substances. The 20 amino acids can be divided into two groups, the essential and the non-essential amino acids. There are eight essential amino acids, isoleucine, leucine, lysine, methionine, phenylalanine, … Amino acids list
Phenylalanine Like other amino acids, phenylalanine is involved in the production of other amino acids. Especially in the liver, phenylalanine can be converted to tyrosine. For this purpose, however, it must be available in sufficient quantities. Phenylalanine is also needed for the production of messenger substances such as noradrenaline. Threonine Threonine, like other essential amino … Phenylalanine | Amino acids list
Glycine Glycine can be produced in the body from other amino acids and is the smallest amino acid with a simple structure. It is a component of haemoglobin metabolism (haemoglobin transports oxygen in the blood), is involved in the energy supply in creatine metabolism and plays an important role in skin regeneration, hair formation and … Glycine | Amino acids list
