Isoket®

Active ingredient Isosorbiddinitrate (ISDN) Mode of action Isosorbide dinitrate belongs to the group of nitrates from which nitric oxide (NO) can be released after absorption into the body. Nitric oxide leads to dilation of blood vessels (vasodilation), especially of the veins and larger coronary arteries. Nitrates thus lead to a reduction in the so-called preload, … Isoket®

Contraindications | Isoket®

Contraindications Isosorbide dinitrate must not be used in cases of known hypersensitivity to the active substance, acute circulatory failure, cardiogenic shock, systolic blood pressure < 90 mmHg (hypotension), hypertrophic obstructive cardiomyopathy (HOCM), and narrowing of the mitral valve or aortic valve (stenosis). Interactions A combination of ISDN and drugs to treat erectile dysfunction from the … Contraindications | Isoket®

Vasodilation: Function, Role & Diseases

Vasodilation is a widening of the vessels by relaxation of the vascular smooth muscle. This smooth muscle is controlled by the two antagonists, sympathetic and parasympathetic, in the autonomic nervous system. In anaphylactic (allergic) shock, vasodilation of life-threatening proportions is present. What is vasodilation? Vasodilation is a widening of the vessels due to relaxation of … Vasodilation: Function, Role & Diseases

Atacand PLUS

Candesartan, candesartan cilexetil, angiotensin II receptor antagonists, hydrochlorothiazide, diuretic, antihypertensive, antihypertensiveAtacand PLUS® is a drug for the treatment of high blood pressure (hypertension) in adults. It is a combined preparation of the two active ingredients candesartan and hydrochlorothiazide. Candesartan dilates the blood vessels, while hydrochlorothiazide has a draining effect. Both lead to a decrease in … Atacand PLUS