Products Bisphosphonates are commercially available in the form of film-coated tablets and as injection and infusion preparations. They are also combined fixed with vitamin D3. Their effects on bone were described in the 1960s. Etidronate was the first active ingredient to be approved (out of trade). Structure and properties Bisphosphonates contain a central carbon atom … Bisphosphonates Effects and Side Effects
Products Tacalcitol is commercially available as an ointment and lotion (Curatoderm). It has been approved in many countries since 1995. Structure and properties Tacalcitol (C27H44O3, Mr = 416.6 g/mol) is a derivative of vitamin D3. It is lipophilic and is present in drugs as tacalcitol monohydrate. Effects Tacalcitol (ATC D05AX04) inhibits the proliferation of keratinocytes … Tacalcitol
Products Calcifediol was approved in the United States in 2016 and in many countries in 2020 in extended-release capsule form (Rayaldee). Structure and properties Calcifediol (C27H44O2, Mr = 400.6 g/mol) is a hydroxylated derivative of vitamin D3 (cholecalciferol). It is 25-hydroxycholecalciferol or 25-hydroxyvitamin D3. Calcifediol is present in the drug as calcifediol monohydrate, a white … Calcifediol
Products Calcipotriol is commercially available as a fixed combination with betamethasone dipropionate as a gel, ointment, and foam (Xamiol, Daivobet, Enstilar, generics). Structure and properties Calcipotriol (C27H40O3, Mr = 412.60 g/mol) is a synthetic derivative of natural vitamin D3 (cholecalciferol). It exists as a white crystalline powder. Effects Calcipotriol (ATC D05AX02) has antiproliferative, anti-inflammatory, and … Calcipotriol
Products Calcium acetate is commercially available in the form of capsules and tablets in various strengths (Calcium Acetate Phosphate Binder Bichsel, Calcium Acetate Salmon Pharma, AcetaPhos, Renacet). It has been approved in many countries since 1992. Structure and properties Calcium acetate exists as calcium diacetate (C4H6CaO4, Mr = 158.2 g/mol), a white, hygroscopic powder that … Calcium Acetate
Products Calcium carbonate is commercially available as a drug in the form of tablets, capsules, effervescent tablets, chewable tablets, lozenges, and oral suspension, among others. Some products are combination preparations, for example with vitamin D3 or other antacids. Structure and properties Calcium carbonate (CaCO 3 , M r = 100.1 g/mol) exists in pharmacopoeia quality … Calcium Carbonate
Products Vitamin K2 is commercially available as a dietary supplement in the form of capsules and drops, among others. It is also combined with vitamin D3 fix (D3K2). It occurs naturally, for example, in chicken, egg yolks, dairy products, certain cheeses, and liver, and is produced by microorganisms during fermentation. It is also found in … Vitamin K2 Health Benefits
Structure and properties Polypeptide composed of 84 amino acids Synthesis and release Formation in the parathyroid glands Effects Bone resorption by activation of osteoclasts: increase in blood calcium levels Effect on kidney: Decrease in phosphate reabsorption: decrease in blood phosphate level. Decrease in calcium excretion: increase the level of calcium in the blood. Stimulation of … Parathyroid Hormone
Products Cholecalciferol (colecalciferol) is commercially available as a monopreparation as an alcoholic or oily-based solution and in tablet and capsule form. Numerous combination preparations with other vitamins and minerals, and especially with calcium, are available. Cholecalciferol has been approved in many countries since 1938 and is also available as a dietary supplement. See also vitamin … Cholecalciferol (Vitamin D3)
Calcigen® D is a vitamin-mineral combination preparation consisting of calcium carbonate 1500 mg (equivalent to 600 mg calcium) and vitamin D3 (cholecalciferol) 400 I. E to be taken twice daily. If the preparation is used during pregnancy, however, it may only be taken once a day at most. It is available from a pharmacy but … Calcigen® D
Pregnancy and lactation Calcigen® D can be used during pregnancy and lactation to correct calcium and vitamin D3 (cholecalciferol) deficiency. However, it is important that a maximum of one tablet per day is taken, so that a daily dose of 1500 mg calcium and 600 I. U. vitamin D3 (cholecalciferol) is not exceeded. When breastfeeding, … Pregnancy and lactation | Calcigen® D
When should one take the BCAA? In order for BCAAs to have the best effect, the time of taking them must be well coordinated. Otherwise there is only a partial exhaustion of the BCAAs pool. In general, one can say that there are two important points in time for taking BCAAs. On the one hand … When should one take the BCAA? | BCAA for muscle building
