Tramazoline

Products

Tramazoline is commercially available in the form of nasal sprays, nasal drops, and as eye drops. The drugs are not registered in many countries.

Structure and properties

Tramazoline (C13H17N3, Mr = 215.3 g/mol) is an imidazoline derivative structurally related to naphazoline, oxymetazoline, and xylometazoline.

Effects

Tramazoline (ATC S01GA) is a vasoconstrictor and decongestant. The effects are due to agonism at alpha receptors.

Indications

For symptomatic treatment of noninfectious forms of conjunctivitis, to decongest the nasal mucosa in rhinitis.