Products
Triclocarban is commercially available as a drug solution (Septivon). It has been approved in many countries since 1975. It is also used for personal care products and plastics, among other uses.
Structure and properties
Triclocarban (C13H9Cl3N2O, Mr = 315.6 g/mol) exists as a white powder that is insoluble in water.
Effects
Triclocarban (ATC D08A102) has disinfectant properties.
Indications
As a disinfectant skin wash for cleaning minor superficial injuries and hand cleansing.
Dosage
According to the professional information.
Contraindications
- Hypersensitivity
- Application to the eye or in the immediate vicinity of the eye
- Application on large injured skin areas
- Application on children
Full precautions can be found in the drug label.
Interactions
Hard water may slightly reduce efficacy against Gram-negative bacteria. Proteins may slightly reduce efficacy.
Adverse effects
The most common possible adverse effects include local reactions such as a burning sensation, itching, dryness, flaking, and redness. Triclocarban, like triclosan, is controversial for environmental and toxicological reasons. For example, it can accumulate in the environment, in plants and animals (including humans) and harm aquatic organisms. Triclocarban is further an endocrine disruptor.
