Ursodeoxycholic Acid

Products

Ursodeoxycholic acid is available in many countries in various dosage forms and has been approved since 1978.

Structure and properties

Ursodeoxycholic acid (C24H40O4, Mr = 392.6 g/mol) exists as a white powder that is very sparingly soluble in water. It is a naturally occurring bile acid that can be prepared from bovine bile.

Effects

Ursodeoxycholic acid (ATC A05AA02) has litholytic properties. It can dissolve cholesterol-containing gallstones. It normalizes bile composition and thus can relieve dyspeptic symptoms.

Indications

  • To dissolve cholesterol gallstones
  • Dyspeptic complaints
  • Fat intolerance
  • Flatulence of biliary origin
  • Primary biliary cirrhosis

Dosage

According to the professional information. The drugs are usually taken twice a day (morning and evening).

Contraindications

For complete precautions, see the drug label.

Adverse effects

The most common possible adverse effects include diarrhea and abdominal pain.