In uterine fibroid (synonyms: Myoma of the uterus; Uterus myomatosus; Fibromyoma of the corpus uteri; Fibromyoma of the uterus; Fundus myoma; Uterine myoma; Intramural leiomyoma of the uterus; Leiomyofibroma of the cervix uteri; Leiomyofibroma of the corpus uteri; Multinodular uterine myomatosus; Myoma uteri; Submucosal leiomyoma of uterus; Subserosal leiomyoma of uterus; Uterine fibroid; Uterine posterior wall myoma; Uterine leiomyoma; Uterine myoma; Uterine anterior wall myoma; ICD-10-GM D25. -: Leiomyoma of the Uterus) is the most common benign neoplasm in women that originates from the musculature (myoma) of the uterus (womb). Histologically (by fine tissue), the fibroids are usually leiomyomas.
Classification according to ICD-10-GM:
- ICD-10-GM D25.-: Leiomyoma of the uterus
- Incl: Fibromyoma of the uterus Benign neoplasm of the uterus with morphology code number M889 and malignancy grade /0
- ICD-10-GM D25.0: Submucosal leiomyoma of the uterus.
- ICD-10-GM D25.1: Intramural leiomyoma of the uterus
- ICD-10-GM D25.2: Subserosal leiomyoma of the uterus
- ICD-10-GM D25.9: Leiomyoma of the uterus, unspecified.
Leiomyoma is usually a nodular encapsulated round tumor. Myomas can occur singly (solitary myomas), but often they are distributed in larger numbers in the uterus, which is then called uterus myomatosus.
Leiomyoma can also occur in other organs. Malignant degeneration occurs in only about 0.1% of all leiomyomas.
Frequency peak: The maximum incidence of fibroids is between the ages of 35 and 45. The incidence increases with age until passing through menopause (menopause in women).
The prevalence (disease incidence) is 20-30% of women after the age of 30 in Germany. Leiomyomas do not occur in girls and women after menopause. They frequently affect nulliparae, i.e. women who have not given birth.
Course and prognosis: Only symptomatic fibroids need to be treated. Thus, leiomyomas can lead to chronic lower abdominal pain. If conservative therapies are not effective, hysterectomy (removal of the uterus) should be considered, taking family planning into account. As long as there are no symptoms, the patient must have regular check-ups, because the benign lumps can lead to complications such as urinary tract infections as well as functional disorders of the bladder, bowel or kidneys. Leiomyomas can be recurrent (recurring).
