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Therapeutic targets
- Symptom relief
- Elimination of the pathogens (as far as possible).
- Avoidance of complications (as far as possible)
Therapy recommendations
- Intensive care to support vital functions (circulatory, respiratory).
- Symptomatic therapy (analgesics), antipyretics (antipyretic drugs)) including rehydration (fluid balance).
- Virostasis (use of antivirals as far as possible):
- Crimean-Congo fever – effective given early in individual cases.
- Lassa fever – onset max. on day 6; duration of therapy 10 d.
- Postexposure prophylaxis in Lassa fever – if Lassa infection is clear.
- Dengue fever, consider virostasis if kidney problems.
- West Nile virus, consider interferon alpha.
- Prevention of secondary infections, e.g. pneumonia (antibiosis/antibiotic therapy).