The following are the most important diseases or complications that may be contributed to by Werlhof disease:
Cardiovascular system (I00-I99).
- Intracranial hemorrhage (bleeding within the skull; parenchymal, subarachnoid, sub- and epidural, and supra- and infratentorial hemorrhage)/intracerebral hemorrhage (ICB; cerebral hemorrhage), unspecified
Infectious and parasitic diseases (A00-B99).
- Infections, unspecified; often due to therapy.
Mouth, esophagus (food pipe), stomach, and intestines (K00-K67; K90-K93).
- Bleeding gums
- Gastrointestinal bleeding
Symptoms and abnormal clinical and laboratory findings not elsewhere classified (R00-R99).
- Epistaxis (nosebleed).
Genitourinary system (kidneys, urinary tract – sex organs) (N00-N99).
- Menorrhagia – prolonged and increased menstruation (menstrual bleeding).
Further
- Life-threatening hemorrhage, unspecified; risk increases with age (>60 years: 13% per year)
Often a parallel infestation with Helicobacter pylori is found in the stomach!