Therapeutic target
Increase in platelet count
Therapy recommendations
The American Society of Hematology recommends initiation of glucocorticoid therapy for:
- Platelets <50,000/μl with a marked bleeding tendency.
- Platelets < 30,000/μl with slight bleeding tendency
- Platelets < 20,000/μl in general
Furthermore, note:
- In the absence of success of glucocorticoid therapy, do not continue it for more than 4 weeks.
- Preoperatively, prepartum and in acute bleeding immunoglobulins are to be used, these bring only short-term remissions (3-5 weeks).
- In acute severe bleeding platelet concentrates and / or blood clotting factors are to be used.
- See also under “Further therapy“.
