What side effects can occur during discontinuation? | What are the side effects of valproic acid?

What side effects can occur during discontinuation?

Medication should never be discontinued by the patient on their own, but always in consultation with a doctor. Sometimes side effects make it necessary to discontinue the antiepileptic drug. Regardless of this, discontinuation of the drug can be considered even after the recommended two-year seizure-free period.In any case, discontinuing antiepileptic drugs such as valproate is an individual decision that should be made under the supervision of an experienced neurologist.

The dose of valproic acid should be reduced as gradually as possible, i.e. discontinued. There are no indications of particular side effects when discontinuing valproic acid. However, as with other antiepileptic drugs, withdrawal seizures can occur, especially if the drug is discontinued too quickly.

Lighter types of seizures such as auras can also occur and should stop the withdrawal attempt. The patient should be informed in detail about the discontinuation attempt as well as the possible risks involved and should undergo regular checks to ensure that the attempt is successful and low-risk.