White Spot Disease (Vitiligo): Classification

Classification of vitiligo and characteristics of vitiligo subtypes [guidelines: 1].

Vitiligo types Subtypes Comments
Non-segmental vitiligo (NSV) Often diffuse with symmetrical, acral to a generalized pattern of distribution (acrofacial vitiligo); localizations:

  • Symmetrically on extensor sides of elbows, forearms, and hands, as well as knees, lower legs, and dorsum of feet; flexor sides of wrists; axillae; anal region
  • Acral form involves to a large extent the face, fingers, genitals and dorsum of the foot
  • Back and backs of the legs (much less common).
 Subtyping may not reflect a clear origin of the appearance but is useful information for epidemiologic studies.
Segmental vitiligo (SV) Focal (focal), mucosal, uni-, bi- or multisegmental Further classification by dissemination pattern possible, but not yet standardized.
Mixed form (NSV + SV) Depending on the severity of SV Usually, the SV proportion is more severe in mixed vitiligo.
Unclassified form Focal at onset, multifocal asymmetric non-segmental, mucosal (one site) The purpose of this category is to allow a definitive classification to be made after a sufficient period of observation (and investigation, if necessary).