Laboratory parameters of 1st order – obligatory laboratory tests.
- Small blood count
- Differential blood count
- Coagulation parameters – bleeding time [↑], PTT [↑], Quick [normal].
- Determination of clotting factors:
- VWF (von Willebrand factor; synonyms: Clotting factor VIII-associated antigen or von Willebrand factor antigen, vWF-Ag).
- VIII (hemophilia A)
- IX (Hemophilia B)
Laboratory parameters 2nd order – depending on the results of the history, physical examination and mandatory laboratory parameters.
- Ristocetin cofactor – by forming a ristocetin cofactor/vWF antigen quotient, vWS type 2 can be diagnosed with a high degree of reliability.
- Von Willebrand multimer analysis – for subtyping.
- Genetic diagnostics/mutation analysis (vWF)
