In the root of the sleeping berry, approximately 1.33% of withanolides and 0.13%-0.31% of alkaloids are present. In comparison, in the leaves, the concentrations of withanolides and alkaloids are increased by 1.8 times and 2.6 times, respectively.The extracts used in dietary supplements are usually standardized to 1.5% withanolides . The German Federal Institute for Risk Assessment (BfR) gives a daily dosage recommendation of 4.5 mg to 7.5 mg of withanolides. A large number of products containing sleeping berries are offered on the Internet. Depending on the consumption recommendation, the intake of withanolides varies from 5 mg to 61 mg.
