Yersiniosis: Drug Therapy

Therapeutic targets

  • Rehydration (fluid balance).
  • Elimination of pathogens
  • Avoidance of complications

Therapy recommendations

  • Antibiotics should be avoided. As a rule, the course is self-limiting, i.e., ending without external influences. Antibiosis (ciprofloxacin (fluoroquinolones), first-line agent; doxycycline, if necessary) is recommended only for the following indication:
    • Severe courses with impending sepsis.
  • Symptomatic therapy including fluid replacement – oral rehydration for signs of dehydration (fluid deficiency; > 3% weight loss): administration of oral rehydration solutions (ORL), which should be hypotonic, between meals (“tea breaks”) for mild to moderate dehydration.
  • Compensation of electrolyte losses (blood salts).
  • See also under “Further therapy“.