Therapeutic target
- Slowing of progression (progression).
- Improvement of survival
Therapy recommendations
- Drug therapy is not possible!
- Absolute alcohol abstinence (abstaining from alcohol).
- Adequate nutrition (with positive nitrogen balance).
- Intensive therapy if necessary
- For alcoholic hepatitis, the following agents can be used (see below).
- In the final stages of cirrhosis, liver transplantation (LTx) may be considered.
Active ingredient group | Active ingredients | Special features |
Glucocorticoids | Prednisone | Therapy for 4 weeks, then taper off Success under glucocorticoids is evident when serum bilirubin drops 25% within the first 6-9 days |
TNF-α inhibitor | Infliximab | Risk of reactivation of tuberculosis |