Zika Virus Infection: Symptoms, Complaints, Signs

The following symptoms and complaints may indicate Zika virus infection:

Main symptoms

  • Aphtae on the lip
  • Arthralgias (joint pain) – especially in the wrists and ankles, knees (about 2/3 of patients).
  • Pronounced feeling of illness
  • Emesis (vomiting)
  • Fever
  • Hemospermia (blood in the semen)
  • Skin rash (maculopapular exanthema/ blotchy rash appearing with small nodules).
  • Conjunctivitis (conjunctivitis).
  • Photophobia (sensitivity to light)
  • Headache
  • Lymphadenopathy (enlargement of lymph nodes), even in unusual places, such as behind the auricle
  • Myalgias (muscle pain)
  • Chills

Other indications

  • The above symptoms occur in a period of 3-12 days (usually 3-7 days) after an infectious mosquito bite and last up to a week.
  • Approximately 80% of all Zika infections are asymptomatic!
  • A case series of 13 children showed that a normal head circumference at birth does not exclude severe brain damage caused by Zika virus: only months after birth growth disturbances (slight reduction in head circumference with transition to microencephaly) appeared.