ExplanationDefinition
Zoloft® is an antidepressant that belongs to the group of selective serotonin reuptake inhibitors (SSRIs). It is characterized in particular by the fact that it does not attenuate (sedate) and is also used for a variety of disorders.
Trade names
Gladem®Zoloft®Sertralin-ratiopharm®.
Chemical name
(1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-terahydro-N-methyl-1-naphtylamine
Active ingredient
Sertraline
- Depression
- OCD
- Panic Attack
- Posttraumatic Stress Disorder (PTSD)
- Generalized anxiety disorder
Dosage form
- TabletsFilm coated tablets
- Solution
An antidepressant intervenes in the brain metabolism. The theory here is that there are often too few of certain messenger substances. The transmitter substance serotonin is of particular importance here.
In contrast to other antidepressants, Zoloft® is a drug specialized in serotonin. Simply put, transmitters function in such a way that they are released from one cell to trigger an effect on another cell, i.e. to transmit a message. Afterwards, they usually return to their cells and wait for the next application. However, serotonin reuptake inhibitors now ensure that this special messenger substance remains outside the cell for longer and can thus do its “work” for longer. –> Continue to Antidepressant effect.
Dosage
Zoloft® is available in 50mg and 100mg dosages. The starting dose is 50mg per day. The maximum dose should not exceed 200mg per day.
Side effect
Only very common (>10%) to common (1-10%) side effects are listed; occasional, rare or very rare side effects are not listed! Common side effects of Zoloft® are (especially at the beginning of therapy): Rare side effects:
- Nausea and vomiting
- Diarrhea
- Inner restlessness
- Insomnia
- Headaches
- Swindle
- Loss of appetite
- Sexual dysfunction
- Possible liver value increases (temporary)
- Orgasmic Disorders
Interaction
Overall, Zoloft® (unlike other SSRIs) appears to rarely interact:
- Neuroleptics: Possibly the blood levels of neuroleptics can increase. This increases the risk of side effects such as extrapyramidal disorders.
- Lithium: The simultaneous administration of lithium appears to increase the probability of side effects.
