Zuclopenthixol

Products

Zuclopenthixol is commercially available in the form of dragées, as drops, and as a solution for injection (Clopixol). It has been approved in many countries since 1977.

Structure and properties

Zuclopenthixol (C₂₂H₂₅ClN₂OS, M_r = 400.7 g/mol) is present in drugs as zuclopenthixol dihydrochloride, zuclopenthixol acetate, or zuclopenthixol decanoate. Zuclopenthixol decanoate is a yellow, viscous, oily liquid that is very slightly soluble in water.

Effects

Zuclopenthixol (ATC N05AF05) has antipsychotic and sedative properties.

Indications

• Schizophrenias and other psychoses
• Manic phase of manic-depressive psychoses.
• Severe confusional and agitated states in senile demented or arteriosclerotic patients and in oligophrenia