The following are the most important diseases or complications that may be contributed to by myasthenia gravis:
Musculoskeletal system and connective tissue (M00-M99).
- Cholinergic crisis – muscle weakness resulting from excessive doses of cholinesterase inhibitors; signs include increased tearing and salivation, diarrhea (diarrhea), and tachycardia (heartbeat too fast: >100 beats per minute); mortality risk (risk of death) is increased
- Myasthenic crisis – life-threatening exacerbation of symptoms, possibly with respiratory insufficiency (weakness of respiratory muscles) to failure of respiratory muscles or aspiration (eg. Ingestion of foreign bodies → aspiration pneumonia); frequent triggers are infections, medication intake errors, insufficient or too early terminated immunosuppression; particularly at risk are patients with bulbar and respiratory symptoms who have a vital capacity (VC/characteristic for the function of the lungs) below 1,000 ml in women or 1,500 ml in men, as well as multimorbid (affected by many diseases at the same time); mortality (mortality) is 5%.
