Silymarin (Milk Thistle Fruit Extract): Interactions

There are moderate interactions between silymarin and drugs that are metabolized (metabolized) in the liver via cytochromes P450 2C9. Concomitant use of silymarin and these drugs may slow their breakdown and increase their effects and side effects. Furthermore, there are interactions between milk thistle and glucuronidated drugs. In this case, the effect of the drugs … Read more

Other Vital Substances

The following are active substances (micronutrients) that also perform important tasks in the body: In addition to macronutrients (carbohydrates, proteins, fats) and the well-known vital substances – vitamins, minerals, trace elements, essential fatty acids, essential amino acids, and bioactive substances – there are numerous compounds in foods that also perform important vitamin-like functions in the … Read more

Winter Cherry (Withania Somnifera): Definition

Sleepberry (Withania somnifera) is a commonly used medicinal plant in India and belongs to the nightshade family (Solanaceae). The plant, which has been used for 3,000 years, is also known as ashwagandha, winter cherry or Indian ginseng. The herbaceous plant prefers dry, stony soil with sun to partial shade and can reach a height of … Read more

Winter Cherry (Withania Somnifera): Supply Situation

In the root of the sleeping berry, approximately 1.33% of withanolides and 0.13%-0.31% of alkaloids are present. In comparison, in the leaves, the concentrations of withanolides and alkaloids are increased by 1.8 times and 2.6 times, respectively.The extracts used in dietary supplements are usually standardized to 1.5% withanolides . The German Federal Institute for Risk … Read more

Silymarin (Milk Thistle Fruit Extract): Functions

Traditionally, silymarin has been used as a tea or dry extract to treat diseases of the liver, gallbladder, and spleen. It is now one of the best-studied phytochemicals.Based on clinical data, silymarin is used supportively for the following conditions: Alcohol-related liver disease Cirrhosis of the liver Acute and chronic hepatitis Liver disease induced by drugs, … Read more