Sleeping Pills: Effects, Side Effects, Dosage and Uses

Products Sleeping pills are most commonly taken in the form of tablets (“sleeping pills“). In addition, melting tablets, injectables, drops, teas and tinctures are also available, among others. The technical term hypnotics is derived from Hypnos, the Greek god of sleep. Structure and properties Within the sleeping pills, groups can be identified which have a … Sleeping Pills: Effects, Side Effects, Dosage and Uses

Lemborexant

Products Lemborexant was approved in the United States in 2019 in film-coated tablet form (Dayvigo). This as the second agent in the orexin receptor antagonist group. Structure and properties Lemborexant (C22H20F2N4O2, Mr = 410.42 g/mol) is a pyrimidine and pyridine derivative. It exists as a white powder and is practically insoluble in water. Effects Lemborexant … Lemborexant

Almorexant

Products Almorexant is not commercially available. Clinical development was discontinued by Actelion and GlaxoSmithKline (GSK) in 2011 due to adverse effects. Structure and properties Almorexant (C29H31F3N2O3, Mr = 512.6 g/mol) is a tetrahydroisoquinoline derivative. It is structurally related to the opioid methopholine. Effects Almorexant has sleep-inducing properties. It is a selective and dual antagonist at … Almorexant