Products Melatonin is commercially available in the form of sustained-release tablets (Circadin, Slenyto). It was approved as a prescription drug in the EU in 2007 and in many countries in 2009. Melatonin may also be included in magistral formulations. Slenyto was registered in many countries in 2019. In some countries – for example, the United … Melatonin: Drug Effects, Side Effects, Dosage and Uses
Products Macitentan is commercially available in the form of film-coated tablets (Opsumit). It was approved in the United States in October 2013 and in many countries in 2014. Macitentan was launched as a successor to bosentan (Tracleer) as it loses patent protection. Structure and properties Macitentan (C19H20Br2N6O4S, Mr = 588.3 g/mol) is a brominated pyrimidine … Macitentan
Products Tocilizumab is commercially available as a concentrate for the preparation of an infusion solution and as a solution for injection in a prefilled syringe and in a prefilled pen (Actemra, RoActemra in some countries). It has been approved in many countries since 2008. Structure and properties Tocilizumab is a recombinant humanized IgG1 monoclonal antibody … Tocilizumab
Products Ranibizumab is commercially available as a solution for injection (Lucentis). The drug was approved in the United States and many countries in 2006 and in the EU in 2007. The drug’s high price is controversial, especially when compared with bevacizumab (Avastin), which is structurally and pharmacologically similar. Bevacizumab is not approved for these indications … Ranibizumab
