Xeroderma pigmentosum, also called moonshine disease, is understood by physicians to be a skin disease caused by a genetic defect. Affected individuals exhibit a pronounced UV intolerance and therefore usually have to avoid sunlight completely. The disease is as yet incurable. Xeroderma pigmentosum is a very rare, genetic disease of the skin and mucous membranes, … Xeroderma Pigmentosum: Causes, Symptoms & Treatment
Xeroderma pigmentosum is an inherited disease caused by defective repair mechanisms of DNA repair during cell division. These defects lead to increased light sensitivity (photosensitivity) of the skin to UV rays, premature skin aging and an extremely increased risk of skin cancer at a young age. In addition, diseases of the nervous system and the … Xeroderma pigmentosum
Types The classification of Xeroderma pigmentosum was developed from complementation groups. For this purpose, connective tissue cells (fibroblasts) from different XP patients were combined. If the DNA repair defect persisted after the fibroblast fusion, the patients belonged to the same XP type. However, if the DNA repair defect no longer existed, the patients suffered from … Types | Xeroderma pigmentosum
Symptoms of Xeroderma pigmentosum An increased light sensitivity is usually already noticeable in toddlers. Even a short stay in the sun can lead to sunburn, which can last for weeks as an inflammatory redness (erythema). After months or a few years, chronic light damage occurs on skin areas exposed to the sun: light or dark … Symptoms of Xeroderma pigmentosum | Xeroderma pigmentosum
Prophylaxis In order to be able to protect oneself from UV radiation, UV-impermeable protective clothing and sun protection agents help. In addition, glasses or a face mask with UV protection should be worn. The best way to avoid sunlight is to change the day-night rhythm, which should be done in childhood (moonlight children). It has … Prophylaxis | Xeroderma pigmentosum