Products
Cetrimonium bromide is found in lozenges (e.g., Mebu-Lemon, Mebu-Cherry, formerly Lemocin). It has been approved in many countries since 1972.
Structure and properties
Cetrimonium bromide (C19H42BrN, Mr = 364.4 g/mol) is a quaternary amine with a long alkyl radical that is soluble in water. It is a constituent of cetrimide.
Effects
Cetrimonium bromide (ATC D08AJ02) has antiseptic properties.
Indications
As a surface disinfectant. Cetrimonium bromide is approved in combination with other active ingredients for the treatment of inflammation of the mouth and throat and is used, for example, to treat sore throats and aphthae.
Contraindications
- Hypersensitivity
For complete precautions, see the drug label.
Interactions
Anionic surfactants, such as those found in toothpastes, may reverse the effects.
Adverse effects
Possible adverse effects include local or systemic hypersensitivity reactions.