ADH Analogues

Terlipressin

Products Terlipressin is commercially available as an injectable (glypressin, haemopressin). It has been approved in many countries since 1982. Structure and properties Terlipressin (triglycyl lysine vasopressin) is a synthetic analog of vasopressin, the antidiuretic hormone (ADH). It differs from ADH in four amino acids: Terlipressin: Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly ADH: Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly. Effects Terlipressin (ATC H01BA04) has vasoconstrictor properties, … Terlipressin

Desmopressin

Products Desmopressin is commercially available as a solution for injection, in the form of nasal drops, as a nasal spray, tablets, and sublingual tablets (e.g., Minirin, Nocutil, other drugs). It has been approved in many countries since 1973. Structure and properties Desmopressin (C48H68N14O14S2, Mr = 1129.3 g/mol) is present in the drugs as desmopressin acetate, … Desmopressin