Products Favipiravir is approved in Japan in the form of film-coated tablets (Avigan). Structure and properties Favipiravir (C5H4FN3O2, Mr = 157.1 g/mol) is a fluorinated pyrazine carboxamide derivative. It is a prodrug that is biotransformed in cells to the active metabolite favipiravir-RTP (favipiravir-ribofuranosyl-5′-triphosphate), a purine nucleotide analog. Favipiravir exists as a white to slightly yellow … Favipiravir
Products Baloxavirmarboxil was approved in film-coated tablet form in Japan and the United States in 2018 and in many countries in 2020 (Xofluza). Structure and properties Baloxavirmarboxil (C27H23F2N3O7S, Mr = 571.5 g/mol) is a prodrug of baloxavir (synonym: baloxaviric acid). It is converted to the active drug by hydrolysis. It is practically insoluble in water. … Baloxavirmarboxil
Products Galidesivir is in development at BioCryst in the United States and is not yet commercially available. Structure and properties Galidesivir (C11H15N5O3, Mr = 265.27 g/mol) is a prodrug that is metabolized in cells to the active triphosphate. Galidesivir belongs to the nucleoside analogues. It is a derivative of adenosine, to which it is closely … Galidesivir
