Products Vedolizumab was approved in many countries in 2015 as a powder for a concentrate for the preparation of an infusion solution (Entyvio). In 2020, a prefilled pen and prefilled syringe were also registered. Structure and properties Vedolizumab is a humanized IgG1 monoclonal antibody with a molecular mass of 147 kDa. Effects Vedolizumab (ATC L04AA33) … Vedolizumab
Products Natalizumab is commercially available as a concentrate for the preparation of an infusion solution (Tysabri). It has been approved in many countries since 2007. Structure and properties Natalizumab is a recombinant and humanized IgG4ϰ antibody produced in mouse cells that binds to α4-integrins. Effects Natalizumab (ATC L04AA23) has selective immunosuppressive properties. The effects are … Natalizumab