Peripheral Artery Disease: Causes
Pathogenesis (disease development) The cause of chronic peripheral arterial occlusive disease (pAVD) (of the lower extremities) is atherosclerosis (arteriosclerosis, hardening of the arteries) in approximately 95% of cases. In rare cases, there is an inflammatory cause. Atherosclerosis is probably initially caused by fatty streaks. In this process, lipoproteins accumulate in the intima (“inner wall layer”). … Peripheral Artery Disease: Causes