Classification of hemophilia according to factor activity.
Factor activity: factor VIII/factor IX | Assessment | Clinical symptoms |
25-50 % | Subhemophilia | Mostly without symptoms |
5-25 % | Mild hemophilia | Usually asymptomatic, possibly postoperative secondary hemorrhage or hematoma after more severe trauma (injury) |
1-5 % | moderate hemophilia | Bleeding after minor trauma |
< 1 % | severe hemophilia | Spontaneous bleeding |